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Protein Overview: CG6225-PB, CG6225-PA

General Information:
Name(s) found: CG6225-PB / FBpp0112137 [FlyBase]
CG6225-PA / FBpp0082118 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6225 (CG6225, FBgn0038072). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8480299..8486588. It has the cytological map location 87C3. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cellular process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6225 (CG6225, FBgn0038072). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8480299..8486588. It has the cytological map location 87C3. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cellular process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 704 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cellular process [IEA]
    Molecular Function: aminopeptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTAKWIWRL ALSILLVVGF VAAEKPTGYH REICQYRKGK HIQPMSVYHN RLMAMREQMQ  60
   61 IRATLQGPEI YGYILPSTDE HLNQEVAARD QRLRYLSGFS GVRAFAAVTS HGAAIWVENR 120
  121 YAQQADGELE CDWEIYLTSG NVSVADWLGS HVHIDKRVGA DPHLVPHSLW VQWERELEDK 180
  181 FLKLVRINTN LVDHIWGDER PEMPKNQVIK VHEKHFAGES WQDKVKELRR RLAHLGCDAM 240
  241 VVTSLTEIAY LLNIRGTDIP YTPVIKSYAV ISRDDIFFYV DHSKISLGID LHLRTDCFNE 300
  301 DCVKIKEYNQ IWSDIRTYAQ IWKRVLVPAP CVQDLGASEA IYTSMPGKIV VWEISPIIFM 360
  361 RAQKNSDEQA GMRRAHIRDG AAICEAMSNM ETRFHTEQWT EEKIKYEVEL WRLSQKHAKG 420
  421 LSLRTVVAYG EHSALPYYIS SNVTNIEVSD QSLLVIESGG QYLEGTTDVS RTFIFGEPTH 480
  481 EMKKAYTNVL AGILHLAQLK FPSDLKPSEV DALVRSMVWK DMTDFPQATG HGIGSFGSVE 540
  541 EPPISVSYGK NSSFHFKQGY FFSSESGYYK RDDFGVRLKN VLEVVDTGHT HPSGARFLAF 600
  601 RDVTMVPYEP KLIDSTLLSA AEKRLLNEYN AKIRNDIGDE LKRLGNMRAF YWMMNQTRHI 660
  661 REYLPEDEYR SATGAGSCGH SASPLILLGL GLMVILSAII PSRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..207] FFAS03 2.76 Creatinase; Creatinase, catalytic (C-terminal) domain
    2 View Details [208..603] PSI-BLAST 77.30103 Prolidase from Pyrococcus furiosus
    3 View Details [604..704] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  2.60615909541559 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3228898238998 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.18503136472662 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.09388149606759 bayes_pls_golite062009
  • DNA binding
    		•  1.92799814679615 bayes_pls_golite062009
  • binding
    		•  1.4562583231987 bayes_pls_golite062009
  • hydrolase activity
    		•  1.43646476372001 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22693836163332 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.89399203910285 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.762255574851485 bayes_pls_golite062009
  • metallopeptidase activity
    		•  0.629480947971878 bayes_pls_golite062009
  • protein binding
    		•  0.170797254754318 bayes_pls_golite062009
  • catalytic activity
    		•  0.148551873544128 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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