Protein Overview: Sbf-PA

General Information:
Name(s) found:	Sbf-PA / FBpp0082003 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|28573077\|ref\|NP_477401.2\| SET domain binding factor, isoform A [Drosophila melanogaster] [NCBI NR] gi\|28381254\|gb\|AAF54700.3\| SET domain binding factor, isoform A [Drosophila melanogaster] [NCBI NR] The gene SET domain binding factor is referred to in FlyBase by the symbol Dmel\Sbf (CG6939, FBgn0025802). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7615013..7622157. It has the cytological map location 86F8. Based on sequence similarity, it is predicted to have molecular function</span>: diacylglycerol binding; protein tyrosine/serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG6939-PA translation from_gene[CG6939 Sbf FBgn0025802] seq_release:3 mol_weight=225093 cds_boundaries:(3R:7,615,672..7,622,175[-]) aa_length:1993 transcript_info:[CG6939-RA seq_release:3] gene_info:[gene symbol:Sbf FBgn0025802 gene_boundaries:(3R:7,6 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VGH9) CG6939-PA [DrosMelano7227.FASTAC.txt] (AE003693) Sbf gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG6939-PA, isoform A [Drosophila melanogaster]gi\|28573077\|ref\|NP_477401.2\| CG6939-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(7615651..7615743,7615803..7615885,7615945..7616069,7616150..7617743,7617806..7619376,7619443..7621478,7621538..7621858,7621928..7622031,7622103..7622157); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref= [fly-100309-contam.fasta] SET domain binding factor CG6939-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG6939-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3R:complement(7615651..7615743,7615803..7615885,7615945..7616069,7616150..7617743,7617806..7619376,7619443..7621478,7621538..7621858,7621928..7622031,7622103..7622157); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:complement(7615651..7615743,7615803..7615885,7615945..7616069,7616150..7617743,7617806..7619376,7619443..7621478,7621538..7621858,7621928..7622031,7622103..7622157); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] SET domain binding factor, isoform A OS=Drosophila melanogaster GN=Sbf PE=2 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3R:complement(7615651..7615743,7615803..7615885,7615945..7616069,7616150..7617743,7617806..7619376,7619443..7621478,7621538..7621858,7621928..7622031,7622103..7622157); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700,FlyMine:FBpp0082003,modMine:FBpp0082003; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(join(11796381..11796435,11796206..11796309,11795816..11796136,11793721..11795756,11792084..11793654,11790428..11792021,11790223..11790347,11790081..11790163,11789929..11790021)); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700,FlyMine:FBpp0082003,modMine:FBpp0082003; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(11796381..11796435,11796206..11796309,11795816..11796136,11793721..11795756,11792084..11793654,11790428..11792021,11790223..11790347,11790081..11790163,11789929..11790021)); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700,FlyMine:FBpp0082003,modMine:FBpp0082003; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] SET domain binding factor, isoform A OS=Drosophila melanogaster GN=Sbf PE=1 SV=3 [DROME.fasta.20160308] FBpp0082003 type=protein; loc=3R:complement(join(11796381..11796435,11796206..11796309,11795816..11796136,11793721..11795756,11792084..11793654,11790428..11792021,11790223..11790347,11790081..11790163,11789929..11790021)); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700,FlyMine:FBpp0082003,modMine:FBpp0082003; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:complement(join(11796381..11796435,11796206..11796309,11795816..11796136,11793721..11795756,11792084..11793654,11790428..11792021,11790223..11790347,11790081..11790163,11789929..11790021)); ID=FBpp0082003; name=Sbf-PA; parent=FBgn0025802,FBtr0082529; dbxref=FlyBase:FBpp0082003,FlyBase_Annotation_IDs:CG6939-PA,GB_protein:AAF54700.3,REFSEQ:NP_477401,GB_protein:AAF54700,UniProt/TrEMBL:Q9VGH9,FlyMine:FBpp0082003,modMine:FBpp0082003; MD5=73bcc4e528e856eec8792e950f481105; length=1993; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1993 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	intracellular signaling pathway [IEA] dephosphorylation [IEA] mitotic cell cycle [IMP]
Molecular Function:	diacylglycerol binding [ISS] protein tyrosine/serine/threonine phosphatase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLADYFVI VGYDSDKEKT ASNVGGQPTC GKIVQRFPEK DWPDTPFIEG IEWFCQPLGW  60
   61 SLSYEKQEPK FFVSVLTDID ANKHYCACLS FHETVAITQT RSVDDEDETI GSSRLLGATP 120
  121 SSMDGITTTS TPASITHHSV MYAPKCLVLI SRLDCAETFK NCLGTIYTVY IENLAYGLET 180
  181 LIGNILGCIQ VPPAGGPQVR FSIGAGDKQS LQPPQSSSLP TTGSGVHFLF KQLGIKNVLI 240
  241 LLCSVMTENK ILFLSKCYWH LTDSCRALVA LMYPFRYTHV YIPILPAPLT EVLSTPTPFI 300
  301 MGIHSSLQTE ITDLLDVIVV DLDGGLVTIP ESLTPPVPIL PSPLWEQTQD LLSMILFPNL 360
  361 AQADLAFPTL ERPSAIAKTD AQIDKELRAI FMRLFAQLLQ GYRSCLTIIR IHPKPVITFH 420
  421 KAGFLGARDL IESEFLFRVL DSMFFTTFVN ERGPPWRSSD AWDELYSSMN ELLKSEAQNR 480
  481 NLVGRTQRFK GYFNFTFPSY FQILTHIQEL GRVLYENEGT LAHISYAQKV LRPPEGAFQR 540
  541 IHQPAFPRIS SEKVELIIQE GIRKNGVPQR FHVTRNQHRI IPMGPRLPEA LDVRPNVQNS 600
  601 ARRLEVLRIC VSYIFENRIT DARKLLPAVM RTLMHRDARL ILCREFFGYV HGNKAVLDHQ 660
  661 QFELVVRFMN KALQKSSGID EYTVAAALLP MSTIFCRKLS TGVVQFAYTE IQDHAIWKNL 720
  721 QFWESTFFQD VQGQIKALYL LHRRQNEHQK EANCVLDEVP LEEPTALEIT AEQLRKSPNI 780
  781 EEEKKAELAK SEESTLYSQA IHFANRMVSL LIPLDVNVDA ASKPKPAFRL EENQSVSNSI 840
  841 MGSHSLSEHS DEGFEENNAL EIGVTVGKTI SRFIDCVCTE GGVTSEHIRN LHDMVPGVVH 900
  901 MHIESLEPVY LEAKRHPHVQ KPKIQTPCLL PGEDLVTDHL RCFLMPDGRE DETQCLIPAE 960
  961 GALFLTNYRV IFKGSPCDPL FCEQVIVRTF PIASLLKEKK ISVLYLAHLD QTLTEGLQLR1020
 1021 SSSFQLIKVA FDPEVTPEQI ESFRKILSKA RHPFDEFEYF AFQSYGTMLQ GVAPLKTKEK1080
 1081 YSTLKGFAKK TLLRGAKKAG FKQKQQTKRK LVSDYDYGSA DAQETQSIDD ELEDGDEFET1140
 1141 QNNAMPRLLT TKDVERMRER SYVQDWKRLG FDAESQRGFR ISNANTSYAT CRSYPAIIVA1200
 1201 PVQCSDAAIM HLGRCFKGQR IPLPTWRHAN GALLIRGGQP NSKSVIGMLK NTTGSTTNAH1260
 1261 HDVTHYPEQD KYFLALINTM PKLTPLALNQ YSGMNLSMSS LMGHSSSDDR QPLTPELSRK1320
 1321 HKNNLDISDG NKSSQGGKGG TMKGNPKNSL AHPFRKMRLY ALGEKSQAKS NMNVDFCADF1380
 1381 IPVDYPDIRQ SRPAFKKLIR ACMPSHNTNE ADGQSFAKMV EQSDWLQQIS SLMQLSGAVV1440
 1441 DLIDLQESSV MLSLEDGSDV TAQLSSIAQL CLDPYYRSLD GFRVLVEKEW LAFGHRFAHR1500
 1501 SNLKPSHANT NIAFAPTFLQ FLDVVHQLQR QFPMAFEFND FYLRFLAYHS VSCRFRTFLF1560
 1561 DCELERSDSG IAAMEDKRGS LNAKHMFGAG GMATNGSDDE CSVYPLDIRS QRAPAPLNRI1620
 1621 GHSIFDYIER QHNKTPIFYN FLYSGDKSVT LRPQNNVAAL DLWCYYTNEE LAQGAPYDLE1680
 1681 VTTVDDEIDL SETKGKRMVI TAGYDNMEKC NPSAYVCLLS EVKQAETERG HLPQKWLQVW1740
 1741 NSLEVPQLEP VARNTSLGNI FVQTHQHKRS TLEIIMKGRL AGYQDKYFHP HRFEKHPYTT1800
 1801 PTNCNHCTKL LWGPVGYRCM DCGNSYHEKC TEHSMKNCTK YKAIDGAVGP PNVNMSQGDT1860
 1861 ASIASSAATT ARTSSHHFYN QFSSNVAENR THEGHLYKRG ALLKGWKQRW FVLDSIKHQL1920
 1921 RYYDTSEDTA PKGIIELAEV QSVTAAQPAQ IGAKGVDEKG FFDLKTSKRI YNFYAINANL1980
 1981 AQEWIEKLQA CLQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..96]	Pfam	26.619789	No description for PF03456.9 was found. No confident structure predictions are available.
2	View Details	[97..332]	Pfam	62.136677	No description for PF02141.12 was found. No confident structure predictions are available.
3	View Details	[333..458]	Pfam	28.920819	No description for PF03455.10 was found. No confident structure predictions are available.
4	View Details	[459..656]	MSA	1.163992	View MSA. No confident structure predictions are available.
5	View Details	[657..840]	MSA	2.044951	View MSA. No confident structure predictions are available.
6	View Details	[841..925]	deduced	N/A	No confident structure predictions are available.
7	View Details	[926..1022]	Pfam	19.086186	No description for PF02893.11 was found. No confident structure predictions are available.
8	View Details	[1023..1660]	PSI-BLAST	144.0	Crystal Structure of Myotubularin-related protein 2 complexed with phosphate
9	View Details	[1661..1868]	PSI-BLAST	15.221849	Crystal Structure of the Human Beta2-Chimaerin
10	View Details	[1869..1993]	PSI-BLAST	20.522879	Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: Sbf-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: