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Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate. Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidyl inositol-4,5-bisphosphate + phosphate. Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate. Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidyl inositol-4-phosphate + phosphate. Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lipid phosphatase activity
Acc: GO:0042577
Aspect: Molecular Function
Desc: Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 33 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042577 - lipid phosphatase activity (interactive image map)
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