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Protein Overview: FBpp0310595, FBp...

General Information:
Name(s) found: FBpp0310595 [FlyBase]
FBpp0310594 [FlyBase]
FBpp0310592 [FlyBase]
Description(s) found:
Found 47 descriptions.
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  • type=protein; loc=2R:join(19553144..19553410,19553474..19553558,19559499..19559611,19561809..19561865,19561937..19562142,19562327..19562386,19562454..19562508,19562630..19562728,19562878..19562988,19563062..19563231,19563301..19563511,19564544..19564711,19564772..19564870,19564928..19565176,19565238..19565460,19565525..19565682,19565741..19566011,19566070..19566212); ID=FBpp0310595; name=Pde8-PK; parent=FBgn0266377,FBtr0344183; dbxref=FlyBase:FBpp0310595,FlyBase_Annotation_IDs:CG45019-PK; MD5=84030bc9374d789a4bf35165a037723e; length=914; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(19553144..19553410,19553474..19553558,19559499..19559611,19561809..19561865,19561937..19562142,19562327..19562386,19562454..19562508,19562630..19562728,19562878..19562988,19563062..19563231,19563301..19563511,19564544..19564711,19564772..19564870,19564928..19565176,19565238..19565460,19565525..19565682,19565741..19566011,19566070..19566212); ID=FBpp0310594; name=Pde8-PI; parent=FBgn0266377,FBtr0344182; dbxref=FlyBase:FBpp0310594,FlyBase_Annotation_IDs:CG45019-PI; MD5=84030bc9374d789a4bf35165a037723e; length=914; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(19553144..19553410,19553474..19553558,19559499..19559611,19561809..19561865,19561937..19562142,19562327..19562386,19562454..19562508,19562630..19562728,19562878..19562988,19563062..19563231,19563301..19563511,19564544..19564711,19564772..19564870,19564928..19565176,19565238..19565460,19565525..19565682,19565741..19566011,19566070..19566212); ID=FBpp0310592; name=Pde8-PA; parent=FBgn0266377,FBtr0344180; dbxref=FlyBase:FBpp0310592,FlyBase_Annotation_IDs:CG45019-PA; MD5=84030bc9374d789a4bf35165a037723e; length=914; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 914 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: two-component signal transduction system (phosphorelay) [IEA]
    mesoderm development [IEP]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity [IDA][ISS]
    two-component response regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCSPSTLPP APSAGQTGER GSLPLDASEK DESRLFCIKL RRSRLRRCSC GGVTLQPPSD  60
   61 GNGSTAGDNL CGQVLLNPLQ TKSEADYEKL STGKKDSIVT VAALGNFTHS VVRRATGSTG 120
  121 TSGTSSSGGN SRPGHRKSSL ALALTPEDEP MDVYQRNLMD LKYPTVLPPN PPLKALLVFH 180
  181 KSDSICEAIT AACQRHQLDV TLVKSKEEAL DTLQKSYATA QCYHLIIIDA RSSKNLDAEH 240
  241 IARTIRHTHG HHLTTIIAVC KKSFFEKDDV LIALLDAGVN RCVAETTNLA MCSVELKQIL 300
  301 HSIIRPHNVM STQQALYTAL HRLKEVVLIT DDLLRIQYAN RATERLLNMR LDEIISKQLE 360
  361 DIFVSDLSTI SEQCKNIKEF DGILTVRRKS QEGIPMHVRV VPVACIGSAP THLIFNFDVP 420
  421 GGQMDFIATL PQPKEAPRGS LHSVRRCSFD VRSIASDGLR RTSLAKLTSL PLEAPITKII 480
  481 NLLSQVQENC SADEARLIDK VLEFLKREGL YSPQMKEIRT DDPIATDLIG ALLTGPSVYS 540
  541 SRRSSNDSII RTGSSTRTAA IVPAKMKSNP IIMELLDESL SWDFDIFKLE EITDYHPLLY 600
  601 LGMEMFRRFD VFATLNIDEN VCKAWLAVIE AHYRKSNTYH NSTHAADVMQ ATGAFITQLT 660
  661 NKDMLVMDRM EEATALIAAA AHDVDHPGRS SAFLCNSNDA LAVLYNDLTV LENHHAAITF 720
  721 KLTLGDDKIN IFKNLDKETY KSARSTIIDM ILATEMTRHF EHLAKFVSVF GGEEPRDHNP 780
  781 QTDEETSILM RRMLIKVADV SNPARPMQFC IEWARRIAEE YFMQTDEEKQ RHLPIVMPMF 840
  841 DRATCSIPKS QIGFIEYIIQ DMMHAWESFI DMPQLITYMQ INYSQWKKYD EQGVNTLAEI 900
  901 MAKQPPVGKM ANSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..168] PSI-BLAST 20.39794 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    2 View Details [169..558] PSI-BLAST 14.69897 Response regulator PleD in complex with c-diGMP
    3 View Details [559..914] PSI-BLAST 103.0 Catalytic domain of cyclic nucleotide phosphodiesterase pde4d

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • cyclase activity
    		•  4.55850369589467 bayes_pls_golite062009
  • phosphorus-oxygen lyase activity
    		•  4.19521126196013 bayes_pls_golite062009
  • adenylate cyclase activity
    		•  3.61776354332136 bayes_pls_golite062009
  • signal transducer activity
    		•  3.46067036099687 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.46067036099687 bayes_pls_golite062009
  • guanylate cyclase activity
    		•  2.52478538563626 bayes_pls_golite062009
  • DNA binding
    		•  2.40455942568472 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.27397473548288 bayes_pls_golite062009
  • transcription factor activity
    		•  1.64787246557234 bayes_pls_golite062009
  • binding
    		•  0.617577664267326 bayes_pls_golite062009
  • receptor activity
    		•  0.577093218389645 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.200362612626285 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0422335506479401 bayes_pls_golite062009
    3
    Term Confidence Notes
  • 3',5'-cyclic-nucleotide phosphodiesterase activity
    		•  4.72905094107626 bayes_pls_golite062009
  • cyclic-nucleotide phosphodiesterase activity
    		•  4.61245226349897 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  3.65984874547256 bayes_pls_golite062009
  • 3',5'-cyclic-AMP phosphodiesterase activity
    		•  3.3591603098704 bayes_pls_golite062009
  • 3',5'-cyclic-GMP phosphodiesterase activity
    		•  2.96981753811593 bayes_pls_golite062009
  • hydrolase activity
    		•  1.22736412056595 bayes_pls_golite062009
  • catalytic activity
    		•  1.07048165010262 bayes_pls_golite062009
  • binding
    		•  0.994379083280533 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.511207383357891 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.432240759268351 bayes_pls_golite062009
  • protein binding
    		•  0.162314119157812 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle