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Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive. Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate. Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3',5'-cyclic-GMP phosphodiesterase activity
Acc: GO:0047555
Aspect: Molecular Function
Desc: Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.
Synonyms:
  • cyclic GMP phosphodiesterase activity
  • GO:0004116
  • 3',5' cyclic-GMP phosphodiesterase activity
  • cyclic 3',5'-GMP phosphodiesterase activity
  • cyclic guanosine 3',5'-monophosphate phosphodiesterase activity
  • cyclic guanosine 3',5'-phosphate phosphodiesterase activity
  • guanosine cyclic 3',5'-phosphate phosphodiesterase activity
  • cGMP phosphodiesterase activity
  • cGMP-PDE
  • 3',5'-cyclic-GMP 5'-nucleotidohydrolase activity
  • cGMP-specific phosphodiesterase activity
Proteins in PDR annotated with:
   This term: 31 [Search]
   Term or descendants: 44 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047555 - 3',5'-cyclic-GMP phosphodiesterase activity (interactive image map)
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