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Protein Overview: DMAP1-PA

General Information:
Name(s) found: DMAP1-PA / FBpp0085546 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene DMAP1 is referred to in FlyBase by the symbol Dmel\DMAP1 (CG11132, FBgn0034537). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16531536..16533370. It has the cytological map location 57A9. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 433 amino acids

    Gene Ontology:
    Cellular Component: NuA4 histone acetyltransferase complex [IDA]
    Biological Process: phagocytosis, engulfment [IMP]
    negative regulation of transcription [IEA]
    Molecular Function: DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSADVRDILD MERANTPEVT RDSFLATKKR NFERTKTASR RPEGMHREVF ALLYTDKKDA  60
   61 PPLLPTDTAL GIGAGYKETK ARLGMKKVRK WEWAPFSNPA RNDSAVFHHW KRVTDNSTDY 120
  121 PFAKFNKQLE VPSYTMTEYN AHLRNNINNW SKVQTDHLFD LARRFDLRFI VMADRWNRQQ 180
  181 HGTKTVEELK ERYYEVVALL AKAKNQTSEK KVFVYDVEHE RRRKEQLEKL FKRTTQQVEE 240
  241 ENMLINEMKK IEARKKERER KTQDLQKLIS QADQQNEHAS NTPSTRKYEK KLHKKKVHQQ 300
  301 PRPSRVDSVV NAIEIGSSGI KFADLRGSGV SLRSQRMKLP ANIGQRKVKA LEQAIQEFKV 360
  361 DPAPPPTEDI CTSFNELRSD MVLLCELRTA LSTCVYEMES LKHQYEAACP GKTLNIPPSL 420
  421 VPIKTEALDN STN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] MSA 3.040968 View MSA. No confident structure predictions are available.
    2 View Details [128..212] FFAS03 1.02 Solution structures of the myb-like DNA binding domain of 4930532D21Rik protein
    3 View Details [213..306] MSA 1.114985 View MSA. No confident structure predictions are available.
    4 View Details [307..433] MSA 3.108996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.86538715425734 bayes_pls_golite062009
  • DNA binding
    		•  4.40186699787632 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.28652307290136 bayes_pls_golite062009
  • transcription factor activity
    		•  3.78935192723648 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.3280771187468 bayes_pls_golite062009
  • binding
    		•  2.92574888336072 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.15328641013602 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.00875399167309 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  1.79220056389243 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  1.79220056389243 bayes_pls_golite062009
  • transcription activator activity
    		•  1.5973137667873 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.30723796612579 bayes_pls_golite062009
  • transcription factor binding
    		•  1.24678737091956 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.04347003489874 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.02922519793573 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.865913662624162 bayes_pls_golite062009
  • chromatin binding
    		•  0.82130998265632 bayes_pls_golite062009
  • protein binding
    		•  0.795494287543952 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.783286434998113 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.765443826551515 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.691780246385357 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.658518317984762 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.442959384060459 bayes_pls_golite062009
  • deacetylase activity
    		•  0.344653113751978 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.201150053959035 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.192832786095412 bayes_pls_golite062009
  • acyltransferase activity
    		•  0.102805841618814 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  0.091184501159848 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0880065228906077 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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