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View Structure Prediction Details

Protein: DMAP1-PA
Organism: Drosophila melanogaster
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DMAP1-PA.

Description E-value Query
Range
Subject
Range
gi|114556092 - gi|114556092|ref|XP_513103.2| PREDICTED: DNA methyltransferase 1 associated protein 1 [Pan troglodyt...
507.0 [0..3] [418..210]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSADVRDILD MERANTPEVT RDSFLATKKR NFERTKTASR RPEGMHREVF ALLYTDKKDA  60
   61 PPLLPTDTAL GIGAGYKETK ARLGMKKVRK WEWAPFSNPA RNDSAVFHHW KRVTDNSTDY 120
  121 PFAKFNK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [128-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLEVPSYTMT EYNAHLRNNI NNWSKVQTDH LFDLARRFDL RFIVMADRWN RQQHGTKTVE  60
   61 ELKERYYEVV ALLAKAKNQT SEKKV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1x58A
Description: Solution structures of the myb-like DNA binding domain of 4930532D21Rik protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
nucleic acid binding 4.28652307290136 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
transcription repressor activity 3.3280771187468 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
sequence-specific DNA binding 2.15328641013602 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00875399167309 bayes_pls_golite062009
histone acetyltransferase activity 1.79220056389243 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.79220056389243 bayes_pls_golite062009
transcription activator activity 1.5973137667873 bayes_pls_golite062009
transcription corepressor activity 1.30723796612579 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
protein deacetylase activity 1.04347003489874 bayes_pls_golite062009
histone deacetylase activity 1.02922519793573 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.865913662624162 bayes_pls_golite062009
chromatin binding 0.82130998265632 bayes_pls_golite062009
protein binding 0.795494287543952 bayes_pls_golite062009
N-acyltransferase activity 0.783286434998113 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.765443826551515 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009
DNA-dependent ATPase activity 0.658518317984762 bayes_pls_golite062009
N-acetyltransferase activity 0.442959384060459 bayes_pls_golite062009
deacetylase activity 0.344653113751978 bayes_pls_golite062009
transcription coactivator activity 0.201150053959035 bayes_pls_golite062009
DNA helicase activity 0.192832786095412 bayes_pls_golite062009
acyltransferase activity 0.102805841618814 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 0.091184501159848 bayes_pls_golite062009
structure-specific DNA binding 0.0880065228906077 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [213-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVYDVEHERR RKEQLEKLFK RTTQQVEEEN MLINEMKKIE ARKKERERKT QDLQKLISQA  60
   61 DQQNEHASNT PSTRKYEKKL HKKKVHQQPR PSRV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [307-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVVNAIEIG SSGIKFADLR GSGVSLRSQR MKLPANIGQR KVKALEQAIQ EFKVDPAPPP  60
   61 TEDICTSFNE LRSDMVLLCE LRTALSTCVY EMESLKHQYE AACPGKTLNI PPSLVPIKTE 120
  121 ALDNSTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle