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Protein Overview: CG15100-PA

General Information:
Name(s) found: CG15100-PA / FBpp0085809 [FlyBase]
Description(s) found:
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  • gi|24655311|ref|NP_611382.1| CG15100 [Drosophila melanogaster] [NCBI NR]
  • gi|21627004|gb|AAF57625.2| CG15100 [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG15100 (CG15100, FBgn0034401). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14734363..14738184. It has the cytological map location 55F7. Based on sequence similarity, it is predicted to have molecular function</span>: methionine-tRNA ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: methionyl-tRNA aminoacylation. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG15100-PA translation from_gene[CG15100 CG15100 FBgn0034401] seq_release:3 mol_weight=112485 cds_boundaries:(2R:13,910,806..13,914,210[-]) aa_length:1022 transcript_info:[CG15100-RA seq_release:3] gene_info:[gene symbol:CG15100 FBgn0034401 gene_bound [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V8N9) CG15100 protein [DrosMelano7227.FASTAC.txt]
  • CG15100-PA [Drosophila melanogaster]gi|24655311|ref|NP_611382.1| CG15100-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(14734588..14735338,14735399..14736550,14736607..14736711,14736770..14737605,14737684..14737805,14737893..14737995); ID=FBpp0085809; name=CG15100-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotat [fly-100309-contam.fasta]
  • CG15100-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(14734588..14735338,14735399..14736550,14736607..14736711,14736770..14737605,14737684..14737805,14737893..14737995); ID=FBpp0085809; name=CG15100-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(14734588..14735338,14735399..14736550,14736607..14736711,14736770..14737605,14737684..14737805,14737893..14737995); ID=FBpp0085809; name=CG15100-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG15100 OS=Drosophila melanogaster GN=CG15100 PE=3 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(14734588..14735338,14735399..14736550,14736607..14736711,14736770..14737605,14737684..14737805,14737893..14737995); ID=FBpp0085809; name=CG15100-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625,FlyMine:FBpp0085809,modMine:FBpp0085809; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(18850388..18850490,18850179..18850300,18849265..18850100,18849102..18849206,18847894..18849045,18847083..18847833)); ID=FBpp0085809; name=CG15100-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625,FlyMine:FBpp0085809,modMine:FBpp0085809; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(18850388..18850490,18850179..18850300,18849265..18850100,18849102..18849206,18847894..18849045,18847083..18847833)); ID=FBpp0085809; name=MetRS-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625,FlyMine:FBpp0085809,modMine:FBpp0085809; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • CG15100 OS=Drosophila melanogaster GN=MetRS PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0085809 type=protein; loc=2R:complement(join(18850388..18850490,18850179..18850300,18849265..18850100,18849102..18849206,18847894..18849045,18847083..18847833)); ID=FBpp0085809; name=MetRS-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625,FlyMine:FBpp0085809,modMine:FBpp0085809; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(18850388..18850490,18850179..18850300,18849265..18850100,18849102..18849206,18847894..18849045,18847083..18847833)); ID=FBpp0085809; name=MetRS-PA; parent=FBgn0034401,FBtr0086627; dbxref=FlyBase:FBpp0085809,FlyBase_Annotation_IDs:CG15100-PA,GB_protein:AAF57625.2,REFSEQ:NP_611382,GB_protein:AAF57625,UniProt/TrEMBL:A1ZBE9,FlyMine:FBpp0085809,modMine:FBpp0085809; MD5=9809eaac4b8e5a104235b0b54db06a17; length=1022; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1022 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: methionyl-tRNA aminoacylation [IEA][ISS]
    Molecular Function: ATP binding [IEA]
    methionine-tRNA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIYTNDGNP LGLQLLMLAK FAKQPVQVQL VNLNDAKYKD LLVLPTLELD NGLRLFSPAA  60
   61 IAKYLFVGKG QQRDEWLEWS ATLLAPALAH HMAVGHKADA NALPVLNALV KKLDDKLKAT 120
  121 PYLAGDKPSA ADIAIWSLLA PDGTLKGAQN VDNLRDWYGR VKALPEVQEV LAEQPLKDLS 180
  181 FNALQQSNRY GGLHHVPLKR LSLADASKLL VDTTPTVADT VTNEEISAAK AAFTYTAPKE 240
  241 IKEERTVLPK PGERNVLITS ALPYVNNVPH LGNIIGCVLS ADIYARYSRS AGYNTLLICG 300
  301 TDEYGTATEN KALAENLTPR EICDKYFELH NAIYRWFGIG FDYFGRTTTQ EQTDIVQEAF 360
  361 KDVLKAGYII TESVEQLLCQ KCDRFLADRF VEGTCPHPGC GYEDARGDQC DKCGKLVNAT 420
  421 ELIRPRCKVC NSAPVLRSSD QLFIDLPKAE PQLKEWVDKS EGGWTHNAKV ITRAWLKEGL 480
  481 KPRCITRDLK WGIPVPHEGF EKKVFYVWFD APFGYVSMTK RYTKEYQQWW QPAKGTDVEL 540
  541 FQFMAKDNVP FHSVVWPSVL LAINKGHTLV SHIMATEYLN YEDGKFSKSR GIGVFGNDAQ 600
  601 ETGIPADVWR FYLASARPEG QDSSFSWNDL AARNNSELLN NLGNFVNRAL VFCEKNFSST 660
  661 VPGVITTQDE LVLLALINRE LRGYINSMEK AKLRDGVRHL LAISRHGNGY MQSQQPWVLL 720
  721 KGTDDQKTRA STIIGLCVNI ACLLANLLFP YMPTTARTLF GQLNAKQTPL NAEKPLVTLL 780
  781 LPAGHQIGKP APLFAKLEQS FIDELKGKYG GAQATNDAAH SQISAADLEK AVQAQADKVR 840
  841 ELKASTKDKA IWQPEVTKLL DLKKQLEEAK KKTATAAAPA ATPAPSNGSQ SVQDLEKAIQ 900
  901 EQGDKVRKLK GSTKDKTVWQ PEVNILLDLK KQLEAVQKAA KAAPAANAAP AASPAATADA 960
  961 AKVKALEDKI AQQAEKVRTL KATGDAAVWK PEVDILLSLK NELAALTGTP VAGGQGKGKK1020
 1021 KK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..248] PSI-BLAST 20.69897 Class omega GST
    2 View Details [249..949] PSI-BLAST 128.0 Methionyl-tRNA synthetase from Pyrococcus abyssi
    3 View Details [950..1022] PSI-BLAST 7.0 No description for 2djvA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • copper ion binding
    		•  2.40748863139548 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.30799114442278 bayes_pls_golite062009
  • binding
    		•  1.78119413208485 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.71351657881838 bayes_pls_golite062009
  • DNA binding
    		•  1.67625823552709 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64654156180867 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.301062636244523 bayes_pls_golite062009
  • protein binding
    		•  0.157273259994554 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  5.54691369460949 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  3.76808520367507 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • binding
    		•  1.63608200808719 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.63574252106186 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.23060777952134 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.30220012698115 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.256582403702199 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle