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Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile). Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: isoleucine-tRNA ligase activity
Acc: GO:0004822
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
Synonyms:
  • isoleucine translase activity
  • isoleucine-tRNA synthetase activity
  • isoleucyl-tRNA synthetase activity
  • isoleucyl-transfer RNA synthetase activity
  • L-isoleucine:tRNAIle ligase (AMP-forming)
  • isoleucine-transfer RNA ligase activity
  • isoleucyl-transfer ribonucleate synthetase activity
Proteins in PDR annotated with:
   This term: 40 [Search]
   Term or descendants: 40 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004822 - isoleucine-tRNA ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
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