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Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp). Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tryptophan-tRNA ligase activity
Acc: GO:0004830
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp).
Synonyms:
  • L-tryptophan-tRNATrp ligase (AMP-forming)
  • tryptophanyl-transfer ribonucleate synthetase activity
  • tryptophanyl-tRNA synthase activity
  • tryptophanyl-transfer ribonucleic acid synthetase activity
  • tryptophanyl-transfer ribonucleic synthetase activity
  • tryptophanyl-transfer RNA synthetase activity
  • tryptophan translase activity
  • L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity
  • tryptophanyl-tRNA synthetase activity
  • TrpRS activity
  • tryptophanyl ribonucleic synthetase activity
  • L-tryptophan:tRNATrp ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 39 [Search]
   Term or descendants: 39 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004830 - tryptophan-tRNA ligase activity (interactive image map)
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