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Protein Overview: Rpt1-PA

General Information:
Name(s) found: Rpt1-PA / FBpp0088021 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Rpt1 is referred to in FlyBase by the symbol Dmel\Rpt1 (CG1341, FBgn0028687). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3539941..3541453. It has the cytological map location 43E7. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus; cellular process; proteolysis. 8 alleles are reported. The phenotype of these alleles is annotated with: intersegmental nerve. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 433 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle, base subcomplex [ISS][NAS]
    cytoplasm [IEA]
    proteasome regulatory particle [IDA][ISS]
    Biological Process: proteolysis [IDA][ISS]
    response to DNA damage stimulus [IMP]
    cellular process [IMP]
    Molecular Function: ATPase activity [ISS]
    ATP binding [IEA]
    endopeptidase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDYLGDDQR KVKHDEKEDK EIKSLDEGDI ELLKTYGQSQ YHKSIKSIEE DIQKAVKQVN  60
   61 ELTGIKESDT GLAPPALWDL AADKQILQNE QPLQVARCTK IINADSDDPK YIINVKQFAK 120
  121 FVVDLADSVA PTDIEEGMRV GVDRNKYQIH IPLPPKIDPT VTMMQVEDKP DVTYSDVGGC 180
  181 KEQIEKLREV VETPLLHPEK FVNLGIEPPK GVLLFGPPGT GKTLCARAVA NRTDACFIRV 240
  241 IGSELVQKYV GEGARMVREL FEMARSKKAC LIFFDEIDAI GGARFDDGAG GDNEVQRTML 300
  301 ELINQLDGFD PRGNIKVLMA TNRPDTLDPA LMRPGRLDRK VEFGLPDQDG RSHIFKIHAR 360
  361 SMSVERDIRF DLLARLCPNS TGAEIRSVCT EAGMFAIRAR RKVATEKDFL EAVKKVIKSY 420
  421 AKFSATPRYM TYN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..433] PSI-BLAST 73.0 VCP/p97


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle