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Protein Overview: STA5A_RAT

General Information:
Name(s) found: STA5A_RAT [Swiss-Prot]
Description(s) found:
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  • gi|8394373|ref|NP_058760.1| signal transducer and activator of transcription 5A [Rattus norvegicus] [NCBI NR]
  • gi|2500902|sp|Q62771.1|STA5A_RAT RecName: Full=Signal transducer and activator of transcription 5A; AltName: Full=Mammary gland factor [NCBI NR]
  • gi|1009020|gb|AAA98843.1| signal transducer and regulator of transcription 5a1 [Rattus norvegicus] [NCBI NR]
  • Signal transducer and activator of transcription 5A OS=Rattus norvegicus GN=Stat5a PE=1 SV=1 [Swiss-Prot]
  • (Q62771) Signal transducer and activator of transcription 5A (Mammary gland factor) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):10-88036439;10-88036439;10-88036439 Splice isoform Stat5A1 of Q62771 [hmr_yeast5_DM3-1_pombe.fasta]
  • signal transducer and activator of transcription 5A [HMR_022704-rand.fasta]
  • signal transducer and activator of transcription 5A [Rattus norvegicus]gi|1009020|gb|AAA98843.1| signal transducer and regulator of transcription 5a1gi|2500902|sp|Q62771|ST5A_RAT Signal transducer and activator of transcription 5A (Mammary gland factor) [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Splice Isoform Stat5A1 of Signal transducer and activator of transcription 5A [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_017064) signal transducer and activator of transcription 5a [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • signal transducer and activator of transcription 5A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Signal transducer and activator of transcription 5A (Mammary gland factor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • signal transducer and regulator of transcription 5a1 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SPLICE ISOFORM 1 OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Stat5a Isoform Stat5A1 of Signal transducer and activator of transcription 5A [rat-ipi-250309-contam.fasta]
  • Isoform Stat5A1 of Signal transducer and activator of transcription 5A OS=Rattus norvegicus GN=Stat5a [011711_HMR.fasta]
  • Signal transducer and activator of transcription 5A OS=Rattus norvegicus GN=Stat5a PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 793 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][IEA]
    cytoplasm [UNKNOWN][IDA]
    Biological Process: peptidyl-tyrosine phosphorylation [UNKNOWN]
    lipid storage [UNKNOWN]
    prostate gland epithelium morphogenesis [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN]
    positive regulation of gamma-delta T cell differentiation [UNKNOWN]
    positive regulation of lymphocyte differentiation [UNKNOWN]
    positive regulation of survival gene product expression [UNKNOWN]
    transcription from RNA polymerase II promoter [IDA]
    lactation [UNKNOWN][IEP]
    negative regulation of erythrocyte differentiation [UNKNOWN]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    epithelial cell differentiation involved in prostate gland development [UNKNOWN]
    positive regulation of multicellular organism growth [UNKNOWN]
    JAK-STAT cascade [UNKNOWN][IDA]
    T cell homeostasis [UNKNOWN]
    positive regulation of natural killer cell differentiation [UNKNOWN]
    response to ethanol [IEP]
    cytokine-mediated signaling pathway [UNKNOWN]
    Peyer's patch development [UNKNOWN]
    positive regulation of mast cell proliferation [UNKNOWN]
    mammary gland involution [IDA]
    reproductive process in a multicellular organism [IEP]
    positive regulation of mast cell differentiation [UNKNOWN]
    signal transduction [IEA]
    T cell differentiation in the thymus [UNKNOWN]
    positive regulation of inflammatory response [UNKNOWN]
    regulation of transcription, DNA-dependent [IEA][TAS]
    female pregnancy [UNKNOWN]
    development of secondary female sexual characteristics [UNKNOWN]
    development of secondary male sexual characteristics [UNKNOWN]
    positive regulation of activated T cell proliferation [UNKNOWN]
    response to peptide hormone stimulus [UNKNOWN]
    positive regulation of B cell differentiation [UNKNOWN]
    positive regulation of mitotic cell cycle [UNKNOWN]
    regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    positive regulation of natural killer cell mediated cytotoxicity [UNKNOWN]
    luteinization [UNKNOWN]
    positive regulation of interleukin-2 biosynthetic process [UNKNOWN]
    mammary gland development [UNKNOWN]
    regulation of epithelial cell differentiation [UNKNOWN]
    natural killer cell differentiation [UNKNOWN]
    negative regulation of apoptosis [UNKNOWN]
    negative regulation of mast cell apoptosis [UNKNOWN]
    regulation of cell adhesion [UNKNOWN]
    response to nutrient levels [IEP]
    regulation of steroid metabolic process [UNKNOWN]
    Molecular Function: DNA binding [UNKNOWN]
    transcription factor activity [IDA][IEA][TAS]
    protein binding [UNKNOWN][IEA]
    calcium ion binding [IEA]
    double-stranded DNA binding [IDA]
    sequence-specific DNA binding [IDA]
    signal transducer activity [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGWIQAQQL QGDALRQMQV LYGQHFPIEV RHYLAQWIES QPWDAIDLDN PQDRGQATQL  60
   61 LEGLVQELQK KAEHQVGEDG FVLKIKLGHY ATQLQNTYDR CPMELVRCIR HILYNEQRLV 120
  121 REANNCSSPA GVLVDAMSQK HLQINQTFEE LRLITQDTES ELKKLQQTQE YFIIQYQESL 180
  181 RIQAQFGQLA QLNPQERMSR ETALQQKQVS LETWLQREAQ TLQQYRVELV EKHQKTLQLL 240
  241 RKQQTIILDD ELIQWKRGQQ LAGNGGPPEG SLDVLQSWCE KLAEIIWQNR QQIRRAEHLC 300
  301 QQLPIPGPVE EMLAEVNATI TDIISALVTS TFIIEKQPPQ VLKTQTKFAA TVRLLVGGKL 360
  361 NVHMNPPQVK ATIISEQQAK SLLKNENTRN DYSGEILNNC CVMEYHQATG TLSAHFRNMS 420
  421 LKRIKRADRR GAESVTEEKF TVLFESQFSV GSNELVFQVK TLSLPVVVIV HGSQDHNATA 480
  481 TVLWDNAFAE PGRVPFAVPD KVLWPQLCEA LNMKFKAEVQ SNRGLTKENL VFLAQKLFNR 540
  541 RSNHLEDYNS MSVSWSQFNR ENLPGWNYTF WQWFDGVMEV LKKHHKPHWN DGAILGFVNK 600
  601 QQAHDLLINK PDGTFLLRFS DSEIGGITIA WKFDSPDRNL WNLKPFTTRD FSIRSLADRL 660
  661 GDLNYLIYVF PDRPKDEVFA KYYTPVLAKA VDGYVKPQIK QVVPEFVNAS ADAGANATYM 720
  721 DQAPSPVVCP QAHYNMYPPN PDPVLDQDGE FDLDETMDVA RHVEELLRRP MDSLDPRLSP 780
  781 PAGLFTSARS SLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle