Protein Overview: FURIN_RAT

General Information:
Name(s) found:	FURIN_RAT [Swiss-Prot]
Description(s) found: Found 19 descriptions. SHOW ALL	Furin OS=Rattus norvegicus GN=Furin PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	793 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IDA] [NOT]extracellular space [UNKNOWN] trans-Golgi network [UNKNOWN][IEA] trans-Golgi network transport vesicle [UNKNOWN][IEA] membrane raft [UNKNOWN][IEA] integral to membrane [IEA] Golgi apparatus [IEA] Golgi lumen [UNKNOWN] Golgi cisterna [IDA] plasma membrane [IDA] cell surface [UNKNOWN][IEA]
Biological Process:	cell proliferation [UNKNOWN][IEA] regulation of protein catabolic process [UNKNOWN][IEA] signal peptide processing [UNKNOWN][IEA] aging [IEP] nerve growth factor production [UNKNOWN] negative regulation of low-density lipoprotein receptor catabolic process [UNKNOWN][IEA] negative regulation of transforming growth factor-beta1 production [UNKNOWN][IEA] viral assembly, maturation, egress, and release [UNKNOWN][IEA] [NOT]negative regulation of nerve growth factor production [UNKNOWN] proteolysis [IEA] peptide biosynthetic process [UNKNOWN][IEA] nerve growth factor processing [UNKNOWN] protein processing [IDA][IMP] peptide hormone processing [UNKNOWN] protein maturation by peptide bond cleavage [UNKNOWN] regulation of endopeptidase activity [UNKNOWN][IEA] secretion by cell [UNKNOWN][IEA] positive regulation of cell migration [IMP] positive regulation of transforming growth factor beta receptor signaling pathway [IMP]
Molecular Function:	serine-type endopeptidase inhibitor activity [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] metal ion binding [IEA] endopeptidase activity [UNKNOWN] serine-type endopeptidase activity [UNKNOWN][IMP] protease binding [UNKNOWN][IEA] peptide binding [UNKNOWN][IEA] peptidase activity [UNKNOWN][IEA] nerve growth factor binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELRPWLLWV VAAAGALVLL AAEARGQKIF TNTWAVHISG GPAVADSVAR KHGFHNLGQI  60
   61 FGDYYHFWHR AVTKRSLSPH RPRHSRLQRV PQVKWLEQQV AKQRAKRDVY QEPTDPKFPQ 120
  121 QWYLSGVTQR DLNVKEAWAQ GFTGRGIVVS ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP 180
  181 DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNAR IGGVRMLDGE VTDAVEARSL 240
  241 GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFV WASGNGGREH 300
  301 DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKC 360
  361 TESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV 420
  421 SHSYGYGLLD AGAMVALAQN WTTVAPQRKC IIEILAEPKD IGKRLEVRKT VTACLGEPNH 480
  481 ISRLEHVQAR LTLSYNRRGD LAIHLISPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD 540
  541 EDPSGEWVLE IENTSEANNY GTLTKFTLVL YGTASEGLSA PPESSGCKTL TSSQACVVCE 600
  601 EGFSLHQKSC VQRCPPGFTP QVLDTHYSTE NDVEIIRASV CTPCHASCAT CQGPAPTDCL 660
  661 SCPSHASLDP VEQTCSRQSQ SSRESRPQQP PPALRPEVEV EPRLRAGLAS HLPEVLAGLS 720
  721 CLIIALIFGI VFLFLHRCSG FSFRGVKVYT MDRGLISYKG LPPEAWQEEC PSDSEEDEGR 780
  781 GERTAFIKDQ SAL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FURIN_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: