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Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: serine-type endopeptidase inhibitor activity
Acc: GO:0004867
Aspect: Molecular Function
Desc: Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
Synonyms:
  • serine proteinase inhibitor activity
  • serpin activity
  • serine protease inhibitor activity
Proteins in PDR annotated with:
   This term: 429 [Search]
   Term or descendants: 429 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004867 - serine-type endopeptidase inhibitor activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle