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Protein Overview: CASP1_RAT

General Information:
Name(s) found: CASP1_RAT [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Caspase-1 OS=Rattus norvegicus GN=Casp1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 402 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    extracellular region [UNKNOWN][IEA]
    intracellular [IEA]
    Biological Process: response to ATP [UNKNOWN][IEA]
    positive regulation of interleukin-1 alpha secretion [UNKNOWN][IEA]
    positive regulation of interleukin-1 beta secretion [UNKNOWN][IMP]
    myoblast fusion [IMP]
    positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA]
    response to chemical stimulus [UNKNOWN]
    response to organic cyclic substance [IDA]
    memory [IMP]
    microglial cell activation [IMP]
    positive regulation of circadian sleep/wake cycle, non-REM sleep [IMP]
    response to hypoxia [UNKNOWN][IDA]
    cell death [UNKNOWN][IEA]
    induction of apoptosis [UNKNOWN][IEA]
    response to drug [IDA]
    proteolysis [UNKNOWN][IEA]
    apoptosis [IEP]
    positive regulation of apoptosis [IMP]
    positive regulation of cytokine secretion [UNKNOWN][IMP]
    protein processing [UNKNOWN][IEA]
    response to lipopolysaccharide [IMP]
    Molecular Function: protein binding [UNKNOWN][IDA]
    cysteine-type endopeptidase activity [IEA]
    peptidase activity [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADKVLRAKR KQFINSVSVG TINGLLDELL EKRVLNQEEM DTIKLANITV MEKARDLCDH  60
   61 VTKKGPRASQ MFITYICNED CYLAEILELQ SGPSAETVFV TEDSKGGHPF SSETKEKLNK 120
  121 EGGAFPGPSG SLKFCPLEIA QKLWKENHSE IYPIMKTPTR TRLALIICNT DFQHLSRRVG 180
  181 ADVDLREMKL LLQDLGYTVK VKENLTALEM TKELKEFAAC PEHKTSDSTF LVFMSHGLQE 240
  241 GICGITYSNE VADILKVDTI FQMMNTLKCP SLKDKPKVII IQACRGEKQG VVLLKDSVGN 300
  301 SEEGFLTDAI FEDDGIKKAH IEKDFIAFCS STPDNVSWRH PVRGSLFIES LIKHMKEYAW 360
  361 SCDLEDIFRK VRFSFEQPDS RLQMPTTERV TLTKRFYLFP GH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle