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Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. A biological process that results in permanent cessation of all vital functions of a cell. A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The process of cell death in a neuron. The rupture of cell membranes and the loss of cytoplasm. Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. Cell death resulting from activation of endogenous cellular processes. Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cell death
Acc: GO:0008219
Aspect: Biological Process
Desc: A biological process that results in permanent cessation of all vital functions of a cell.
Synonyms:
  • necrosis
Proteins in PDR annotated with:
   This term: 212 [Search]
   Term or descendants: 2805 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008219 - cell death (interactive image map)
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