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Protein Overview: BIRC5_RAT

General Information:
Name(s) found: BIRC5_RAT [Swiss-Prot]
Description(s) found:
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  • gi|9050025|gb|AAF82586.1|AF276775_1 survivin [Rattus norvegicus] [NCBI NR]
  • gi|12585184|sp|Q9JHY7.1|BIRC5_RAT RecName: Full=Baculoviral IAP repeat-containing protein 5; AltName: Full=Apoptosis inhibitor survivin [NCBI NR]
  • gi|11560097|ref|NP_071610.1| baculoviral IAP repeat-containing 5 [Rattus norvegicus] [NCBI NR]
  • Baculoviral IAP repeat-containing protein 5 OS=Rattus norvegicus GN=Birc5 PE=2 SV=1 [Swiss-Prot]
  • (Q9JHY7) Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):None Baculoviral IAP repeat-containing protein 5 [hmr_yeast5_DM3-1_pombe.fasta]
  • baculoviral IAP repeat-containing 5 [HMR_022704-rand.fasta]
  • baculoviral IAP repeat-containing 5 [Rattus norvegicus]gi|12585184|sp|Q9JHY7|BIR5_RAT Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin)gi|9050025|gb|AAF82586.1| survivin [Rattus norvegicus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Baculoviral IAP repeat-containing protein 5 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_022274) baculoviral IAP repeat-containing 5 (survivin) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • baculoviral IAP repeat-containing 5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • survivin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Birc5 Baculoviral IAP repeat-containing protein 5 [rat-ipi-250309-contam.fasta]
  • Baculoviral IAP repeat-containing protein 5 OS=Rattus norvegicus GN=Birc5 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 142 amino acids

    Gene Ontology:
    Cellular Component: interphase microtubule organizing center [UNKNOWN][ISS]
    nuclear chromosome [UNKNOWN]
    chromosome [IEA]
    cytoplasmic microtubule [UNKNOWN][ISS]
    chromosome, centromeric region [UNKNOWN][ISS]
    [NOT]nucleolus [UNKNOWN]
    intracellular [IEA]
    nucleus [UNKNOWN][IDA]
    spindle microtubule [UNKNOWN][ISS]
    cytoskeleton [IEA]
    cytoplasm [UNKNOWN][IDA][ISS]
    centriole [UNKNOWN][ISS]
    cytosol [UNKNOWN][ISS]
    chromosome passenger complex [UNKNOWN][ISS]
    midbody [UNKNOWN][ISS]
    apical plasma membrane [IDA]
    Biological Process: embryonic development [UNKNOWN]
    cytokinesis [UNKNOWN][ISS]
    chromosome segregation [IEA]
    positive regulation of cell cycle [IMP]
    mitosis [IEA]
    microtubule cytoskeleton organization [UNKNOWN]
    response to peptide hormone stimulus [IEP]
    positive regulation of mitotic cell cycle [UNKNOWN][ISS]
    negative regulation of neuron apoptosis [UNKNOWN]
    cell division [UNKNOWN][ISS]
    protein complex localization [UNKNOWN][ISS]
    positive regulation of exit from mitosis [UNKNOWN][ISS]
    G2/M transition of mitotic cell cycle [UNKNOWN][ISS]
    anti-apoptosis [UNKNOWN][IMP][ISS]
    response to drug [IEP]
    negative regulation of caspase activity [UNKNOWN][ISS]
    apoptosis [IEA]
    response to glucocorticoid stimulus [IEP]
    establishment of chromosome localization [UNKNOWN][ISS]
    spindle checkpoint [UNKNOWN][ISS]
    Molecular Function: tubulin binding [UNKNOWN][ISS]
    zinc ion binding [UNKNOWN][ISS]
    identical protein binding [UNKNOWN]
    protein homodimerization activity [UNKNOWN][ISS]
    Ran GTPase binding [UNKNOWN]
    caspase inhibitor activity [UNKNOWN][ISS]
    molecular_function [ND]
    microtubule binding [UNKNOWN][ISS]
    peptidase inhibitor activity [IEA]
    protein binding [UNKNOWN]
    metal ion binding [IEA]
    protein heterodimerization activity [UNKNOWN]
    cofactor binding [UNKNOWN][ISS]
    chaperone binding [UNKNOWN]
    enzyme binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGATALPPIW QMYLKDHRIY TFKNWPFLED CSCTPERMAE AGFIHCPTEN EPDLAQCFFC  60
   61 FKELEGWEPD DNPIEEHRKH SPGCAFLTVK KQVEELTVSE FLKLDKQRAK NKIAKETNNK 120
  121 QKEFEETRRT VRQSIEQLAA LR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] PSI-BLAST 42.0 Anti-apoptotic protein survivin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle