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Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. Any process that modulates the occurrence or rate of cell death by apoptosis. Any process that stops, prevents or reduces the frequency, rate or extent of caspase activity. Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of caspase activity
Acc: GO:0043154
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of caspase activity.
Synonyms:
  • down-regulation of caspase activity
  • downregulation of caspase activity
  • negative regulation of caspase activation
  • inhibition of caspase activation
  • inhibition of caspase activity
  • down regulation of caspase activity
  • GO:0001719
Proteins in PDR annotated with:
   This term: 68 [Search]
   Term or descendants: 68 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043154 - negative regulation of caspase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle