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Protein Overview: gi|123999428, gi...

General Information:
Name(s) found: gi|123999428 [NCBI NR]
gi|123991812 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|123999428|gb|ABM87273.1| ubiquitin specific peptidase 5 (isopeptidase T) [synthetic construct] [NCBI NR]
  • gi|123991812|gb|ABM83956.1| ubiquitin specific peptidase 5 (isopeptidase T) [synthetic construct] [NCBI NR]
    • Organism: synthetic construct
    Length: 835 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELSEEALL SVLPTIRVPK AGDRVHKDEC AFSFDTPESE GGLYICMNTF LGFGKQYVER  60
   61 HFNKTGQRVY LHLRRTRRPK EEDPATGTGD PPRKKPTRLA IGVEGGFDLS EEKFELDEDV 120
  121 KIVILPDYLE IARDGLGGLP DIVRDRVTSA VEALLSADSA SRKQEVQAWD GEVRQVSKHA 180
  181 FSLKQLDNPA RIPPCGWKCS KCDMRENLWL NLTDGSILCG RRYFDGSGGN NHAVEHYRET 240
  241 GYPLAVKLGT ITPDGADVYS YDEDDMVLDP SLAEHLSHFG IDMLKMQKTD KTMTELEIDM 300
  301 NQRIGEWELI QESGVPLKPL FGPGYTGIRN LGNSCYLNSV VQVLFSIPDF QRKYVDKLEK 360
  361 IFQNAPTDPT QDFSTQVAKL GHGLLSGEYS KPVPESGDGE RVPEQKEVQD GIAPRMFKAL 420
  421 IGKGHPEFST NRQQDAQEFF LHLINMVERN CRSSENPNEV FRFLVEEKIK CLATEKVKYT 480
  481 QRVDYIMQLP VPMDAALNKE ELLEYEEKKR QAEEEKMALP ELVRAQVPFS SCLEAYGAPE 540
  541 QVDDFWSTAL QAKSVAVKTT RFASFPDYLV IQIKKFTFGL DWVPKKLDVS IEMPEELDIS 600
  601 QLRGTGLQPG EEELPDIAPP LVTPDEPKAP MLDESVIIQL VEMGFPMDAC RKAVYYTGNS 660
  661 GAEAAMNWVM SHMDDPDFAN PLILPGSSGP GSTSAAADPP PEDCVTTIVS MGFSRDQALK 720
  721 ALRATNNSLE RAVDWIFSHI DDLDAEAAMD ISEGRSAADS ISESVPVGPK VRDGPGKYQL 780
  781 FAFISHMGTS TMCGHYVCHI KKEGRWVIYN DQKVCASEKP PKDLGYIYFY QRVAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] FFAS03 2.01 No description for 2idaA was found.
    2 View Details [83..174] deduced N/A No confident structure predictions are available.
    3 View Details [175..302] PSI-BLAST 26.522879 No description for 2g43A was found.
    4 View Details [303..696] PSI-BLAST 51.0 No description for 2ibiA was found.
    5 View Details [697..835] FFAS03 4.11 Crystal structure of HAUSP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  4.67600289365776 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  4.4180348594722 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  3.7630891050221 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  3.26583764896015 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  3.19070920649427 bayes_pls_golite062009
  • binding
    		•  2.70912934275371 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.63153614400976 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.33467249420642 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.16379604127358 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  2.02075518391878 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.8142438325367 bayes_pls_golite062009
  • peptidase activity
    		•  1.63698757480466 bayes_pls_golite062009
  • hydrolase activity
    		•  1.63137875153947 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.60954084225588 bayes_pls_golite062009
  • DNA binding
    		•  1.58326992587523 bayes_pls_golite062009
  • protein binding
    		•  1.48593945455888 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.29640196277559 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.912215968653949 bayes_pls_golite062009
  • ligase activity
    		•  0.905192840625194 bayes_pls_golite062009
  • transcription factor activity
    		•  0.86907979176353 bayes_pls_golite062009
  • transcription factor binding
    		•  0.852951089928981 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.616289233269298 bayes_pls_golite062009
  • catalytic activity
    		•  0.168711389690753 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.102158909244177 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  5.07217966392719 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  4.8126353299115 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.10679273350501 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  3.4560986989594 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  3.40436079043913 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.7771990270637 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.61392853882074 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  2.27286633653932 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.19567497667142 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.8231786231478 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.6760679925861 bayes_pls_golite062009
  • peptidase activity
    		•  1.65048803233595 bayes_pls_golite062009
  • hydrolase activity
    		•  1.60298601235429 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • DNA binding
    		•  1.57963451746197 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.31567868605385 bayes_pls_golite062009
  • ligase activity
    		•  1.1162212378358 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.04342463991885 bayes_pls_golite062009
  • transcription factor binding
    		•  0.98389047120322 bayes_pls_golite062009
  • transcription factor activity
    		•  0.862666257144125 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.622312347613585 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.178227918600813 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.0641990129080541 bayes_pls_golite062009
    4
    Term Confidence Notes
  • cysteine-type peptidase activity
    		•  6.54685807643041 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  6.39247995905454 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  5.91394445088241 bayes_pls_golite062009
  • peptidase activity
    		•  4.81781093386823 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.44809261178642 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  4.1832081096766 bayes_pls_golite062009
  • hydrolase activity
    		•  3.74079711298952 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.37014194828197 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  2.96735553959103 bayes_pls_golite062009
  • SUMO-specific protease activity
    		•  2.65263825059319 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • binding
    		•  1.92046698500094 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.60603067132723 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.55390581517414 bayes_pls_golite062009
  • DNA binding
    		•  1.52072479259657 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • protein binding
    		•  0.874003454509364 bayes_pls_golite062009
  • transcription factor activity
    		•  0.839300529252518 bayes_pls_golite062009
  • NEDD8-specific protease activity
    		•  0.687958315289315 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.467924587720185 bayes_pls_golite062009
  • kininogen binding
    		•  0.41283715939055 bayes_pls_golite062009
  • calcium-dependent cysteine-type endopeptidase activity
    		•  0.196538841514154 bayes_pls_golite062009
  • transferase activity
    		•  0.0852393573521809 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle