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Protein Overview: NCBP2_RAT

General Information:
Name(s) found: NCBP2_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Nuclear cap-binding protein subunit 2 OS=Rattus norvegicus GN=Ncbp2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 156 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    mRNA cap binding complex [IEA]
    cytoplasm [IEA]
    endoplasmic reticulum [UNKNOWN]
    intrinsic to endoplasmic reticulum membrane [IEA]
    Biological Process: GPI anchor biosynthetic process [UNKNOWN][IEA]
    RNA splicing [ISS]
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IEA]
    mRNA capping [IEA]
    snRNA export from nucleus [ISS]
    gene silencing by RNA [IEA]
    regulation of translational initiation [IEA]
    transport [IEA]
    positive regulation of RNA export from nucleus [ISS]
    mRNA transport [IEA]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]
    RNA 7-methylguanosine cap binding [IEA]
    transferase activity, transferring glycosyl groups [IEA]
    RNA binding [IEA]
    protein binding [IEA]
    mannosyltransferase activity [UNKNOWN]
    alpha-1,2-mannosyltransferase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGLLKALR SDSYVELSEY RDQHFRGDNE EQEKLLKKSC TLYVGNLSFY TTEEQIYELF  60
   61 SKSGDIKKII MGLDKMKKTA CGFCFVEYYS RADAENAMRY INGTRLDDRI IRTDWDAGFK 120
  121 EGRQYGRGRS GGQVRDEYRE DYDAGRGGYG KLAQKQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] PSI-BLAST 32.0 CBP20, 20KDa nuclear cap-binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • RNA cap binding
    		•  5.43390507836051 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.81920018903278 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • snRNA binding
    		•  3.28448936696877 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • U1 snRNA binding
    		•  2.26303528058407 bayes_pls_golite062009
  • structural molecule activity
    		•  1.29928829870122 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07788694919471 bayes_pls_golite062009
  • DNA binding
    		•  0.978604858165557 bayes_pls_golite062009
  • transporter activity
    		•  0.628672636801176 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.505106991526286 bayes_pls_golite062009
  • transcription factor activity
    		•  0.234742017105535 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.182749906784328 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.096231856558874 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.059732432409948 bayes_pls_golite062009
  • snoRNA binding
    		•  0.0568636182001701 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0510390778764699 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0484248928275733 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle