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Protein Overview: ID3_RAT

General Information:
Name(s) found: ID3_RAT [Swiss-Prot]
Description(s) found:
Found 22 descriptions.
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  • DNA-binding protein inhibitor ID-3 OS=Rattus norvegicus GN=Id3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 119 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: neuron differentiation [IEP]
    positive regulation of cell proliferation [TAS]
    response to wounding [IEP]
    regulation of DNA replication [IMP]
    negative regulation of transcription factor activity [UNKNOWN][IEA]
    odontogenesis [UNKNOWN]
    negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    epithelial cell differentiation [UNKNOWN][IEA]
    heart development [UNKNOWN][IEA]
    central nervous system development [UNKNOWN]
    metanephros development [UNKNOWN]
    notochord development [UNKNOWN]
    negative regulation of cell differentiation [TAS]
    negative regulation of transcription [UNKNOWN][IEA]
    positive regulation of apoptosis [IMP]
    regulation of cell cycle [IMP]
    response to protein stimulus [UNKNOWN][IEA]
    Molecular Function: protein domain specific binding [UNKNOWN][TAS]
    protein binding [UNKNOWN]
    transcription regulator activity [IEA]
    transcription repressor activity [UNKNOWN]
    bHLH transcription factor binding [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALSPVRGC YEAVCCLSER SLAIARGRGK SPSAEEPLSL LDDMNHCYSR LRELVPGVPR  60
   61 GTQLSQVEIL QRVIDYILDL QVVLAEPAPG PPDGPHLPIQ TAELTPELVI SKDKRSFCH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] PSI-BLAST 9.39794 SREBP-1a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.39500382187264 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.58751248599889 bayes_pls_golite062009
  • transcription activator activity
    		•  2.5495467409976 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.42306484786159 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.31910036997977 bayes_pls_golite062009
  • transcription corepressor activity
    		•  2.03674713048499 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.07771706364343 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.93846047598021 bayes_pls_golite062009
  • promoter binding
    		•  0.8576109846276 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle