YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that stops, prevents or reduces the frequency, rate or extent of adipocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of spermatid nuclear differentiation. Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. Any process that stops, prevents or reduces the frequency, rate or extent of sporulation. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. Any process that stops, prevents or reduces the frequency, rate or extent of synergid cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast differentiation, the process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The process by which the identity of an organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process by which epiblast cells acquire specialized features of neuroepithelial cells. A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. Any process that stops, prevents or reduces the frequency, rate or extent of pigment cell differentiation. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate determination. Any process that stops, prevents or reduces the frequency, rate or extent of hemocyte differentiation. The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells. Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte differentiation. Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process whereby a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. Any process that stops, prevents or reduces the frequency, rate or extent of antipodal cell differentiation. Any process that stops or decreases the rate or extent of hepatocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of osteoblast differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of epidermal cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of neuron differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of embryo sac central cell differentiation. The process by which an organism retains a population of stem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of embryo sac egg cell differentiation. Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of ovarian cumulus cell differentiation. Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of muscle cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of cell differentiation
Acc: GO:0045596
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.
Synonyms:
  • down regulation of cell differentiation
  • inhibition of cell differentiation
  • downregulation of cell differentiation
  • down-regulation of cell differentiation
Proteins in PDR annotated with:
   This term: 53 [Search]
   Term or descendants: 637 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045596 - negative regulation of cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle