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Protein Overview: PPIC_MOUSE

General Information:
Name(s) found: PPIC_MOUSE [Swiss-Prot]
Description(s) found:
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  • pir||A40047 peptidylprolyl isomerase (EC 5.2.1.8) (cyclophilin C) - mouse [NCBI NR]
  • gi|74223175|dbj|BAE40724.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74203447|dbj|BAE20880.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74191680|dbj|BAE30409.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74151911|dbj|BAE29741.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6679441|ref|NP_032934.1| peptidylprolyl isomerase C [Mus musculus] [NCBI NR]
  • gi|231961|sp|P30412.1|PPIC_MOUSE RecName: Full=Peptidyl-prolyl cis-trans isomerase C; Short=PPIase; Short=Rotamase; AltName: Full=Cyclophilin C [NCBI NR]
  • gi|19483859|gb|AAH25861.1| Peptidylprolyl isomerase C [Mus musculus] [NCBI NR]
  • gi|192899|gb|AAA37511.1| cyclophilin C [NCBI NR]
  • gi|148677963|gb|EDL09910.1| peptidylprolyl isomerase C, isoform CRA_b [Mus musculus] [NCBI NR]
  • Peptidyl-prolyl cis-trans isomerase C OS=Mus musculus GN=Ppic PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):18-53770589 Peptidyl-prolyl cis-trans isomerase C [hmr_yeast5_DM3-1_pombe.fasta]
  • peptidylprolyl isomerase C; cyclophilin C [HMR_022704-rand.fasta]
  • Peptidyl-prolyl cis-trans isomerase C [ipi.MOUSE.v3.06.fasta]
  • peptidylprolyl isomerase C [Mus musculus]gi|19483859|gb|AAH25861.1| Peptidylprolyl isomerase C [Mus musculus]gi|91167|pir||A40047 peptidylprolyl isomerase (EC 5.2.1.8) (cyclophilin C) - mousegi|231961|sp|P30412|PPIC_MOUSE Peptidyl-prolyl cis-trans isom [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Peptidyl-prolyl cis-trans isomerase C [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_008908) peptidylprolyl isomerase C; cyclophilin C [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • peptidylprolyl isomerase C [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase) (Cyclophilin C) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • peptidylprolyl isomerase C, isoform CRA_b [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Peptidylprolyl isomerase C [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • cyclophilin C [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Ppic Peptidyl-prolyl cis-trans isomerase C [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Ppic Peptidyl-prolyl cis-trans isomerase C ENSMUSG00000024538 IPI00130240 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • peptidyl-prolyl cis-trans isomerase C [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00130240.1|SWISS-PROT:P30412|TREMBL:Q3UC73|ENSEMBL:ENSMUSP00000025419|REFSEQ:NP_032934 Tax_Id=10090 Gene_Symbol=Ppic Peptidyl-prolyl cis-trans isomerase C [ipi.MOUSE.fasta.20090209]
  • Peptidyl-prolyl cis-trans isomerase C OS=Mus musculus GN=Ppic [011711_HMR.fasta]
  • sp|P30412|PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C OS=Mus musculus GN=Ppic PE=1 SV=1 [uniprot.sptr.mouse.20130102]
  • tr|Q3UC73|Q3UC73_MOUSE Peptidyl-prolyl cis-trans isomerase OS=Mus musculus GN=Ppic PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Peptidyl-prolyl cis-trans isomerase OS=Mus musculus GN=Ppic PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P30412, Peptidyl-prolyl cis-trans isomerase OS=Mus musculus GN=Ppic PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 212 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: protein folding [IEA]
    Molecular Function: peptidyl-prolyl cis-trans isomerase activity [IEA]
    peptide binding [IEA]
    isomerase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPGPRLLLP AVLCLGLGAL VSSSGSSGVR KRGPSVTDKV FFDVRIGDKD VGRIVIGLFG  60
   61 NVVPKTVENF VALATGEKGY GYKGSIFHRV IKDFMIQGGD FTARDGTGGM SIYGETFPDE 120
  121 NFKLKHYGIG WVSMANAGPD TNGSQFFITL TKPTWLDGKH VVFGKVLDGM TVVHSIELQA 180
  181 TDGHDRPLTD CTIVNSGKID VKTPFVVEVP DW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] PSI-BLAST 60.0 Cyclophilin (eukaryotic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein deacetylase activity
    		•  4.3775483906311 bayes_pls_golite062009
  • histone deacetylase activity
    		•  4.29026678196473 bayes_pls_golite062009
  • peptidyl-prolyl cis-trans isomerase activity
    		•  3.73853378771688 bayes_pls_golite062009
  • cis-trans isomerase activity
    		•  3.66963215732405 bayes_pls_golite062009
  • deacetylase activity
    		•  3.49940864924766 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  3.01511519120932 bayes_pls_golite062009
  • RNA binding
    		•  2.94609837984526 bayes_pls_golite062009
  • isomerase activity
    		•  1.96529188741504 bayes_pls_golite062009
  • binding
    		•  1.46018233647024 bayes_pls_golite062009
  • mRNA binding
    		•  1.45537055700871 bayes_pls_golite062009
  • unfolded protein binding
    		•  1.38124355054041 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.939772862764466 bayes_pls_golite062009
  • catalytic activity
    		•  0.748655649755714 bayes_pls_golite062009
  • hydrolase activity
    		•  0.493806105600863 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.408539130322443 bayes_pls_golite062009
  • drug binding
    		•  0.36339132904137 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.322244688184474 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.286133802341887 bayes_pls_golite062009
  • histone binding
    		•  0.268719695649015 bayes_pls_golite062009
  • protein binding
    		•  0.130251391659493 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle