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Protein Overview: SCYL1

General Information:
Name(s) found: SCYL1 [HGNC (HUGO)]
Description(s) found:
Found 27 descriptions.
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  • SCY1-like 1 (S. cerevisiae) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 808 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWFFARDPVR DFPFELIPEP PEGGLPGPWA LHRGRKKATG SPVSIFVYDV KPGAEEQTQV  60
   61 AKAAFKRFKT LRHPNILAYI DGLETEKCLH VVTEAVTPLG IYLKARVEAG GLKELEISWG 120
  121 LHQIVKALSF LVNDCSLIHN NVCMAAVFVD RAGEWKLGGL DYMYSAQGNG GGPPRKGIPE 180
  181 LEQYDPPELA DSSGRVVREK WSADMWRLGC LIWEVFNGPL PRAAALRNPG KIPKTLVPHY 240
  241 CELVGANPKV RPNPARFLQN CRAPGGFMSN RFVETNLFLE EIQIKEPAEK QKFFQELSKS 300
  301 LDAFPEDFCR HKVLPQLLTA FEFGNAGAVV LTPLFKVGKF LSAEEYQQKI IPVVVKMFSS 360
  361 TDRAMRIRLL QQMEQFIQYL DEPTVNTQIF PHVVHGFLDT NPAIREQTVK SMLLLAPKLN 420
  421 EANLNVELMK HFARLQAKDE QGPIRCNTTV CLGKIGSYLS ASTRHRVLTS AFSRATRDPF 480
  481 APSRVAGVLG FAATHNLYSM NDCAQKILPV LCGLTVDPEK SVRDQAFKAI RSFLSKLESV 540
  541 SEDPTQLEEV EKDVHAASSP GMGGAAASWA GWAVTGVSSL TSKLIRSHPT TAPTETNIPQ 600
  601 RPTPEGVPAP APTPVPATPT TSGHWETQEE DKDTAEDSST ADRWDDEDWG SLEQEAESVL 660
  661 AQQDDWSTGG QVSRASQVSN SDHKSSKSPE SDWSSWEAEG SWEQGWQEPS SQEPPPDGTR 720
  721 LASEYNWGGP ESSDKGDPFA TLSARPSTQP RPDSWGEDNW EGLETDSRQV KAELARKKRE 780
  781 ERRREMEAKR AERKVAKGPM KLGARKLD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..443] PSI-BLAST 50.69897 G-protein coupled receptor kinase 2, N-terminal domain; G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1); G-protein coupled receptor kinase 2
    2 View Details [444..564] FFAS03 1.44 No description for 2ie3A was found.
    3 View Details [565..808] MSA 2.331996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.86908674572736 bayes_pls_golite062009
  • protein binding
    		•  1.62406684925162 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.52597476013849 bayes_pls_golite062009
  • kinase activity
    		•  1.46967868776426 bayes_pls_golite062009
  • protein kinase activity
    		•  1.42061676948467 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.35441545960336 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • clathrin binding
    		•  1.03004613836485 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.940749450143365 bayes_pls_golite062009
  • transferase activity
    		•  0.876865688160088 bayes_pls_golite062009
  • ATP binding
    		•  0.80100967388643 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.766575848955892 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.755570176026019 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.718880569902791 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.718820382381459 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.715416129764882 bayes_pls_golite062009
  • nucleotide binding
    		•  0.708369770220977 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • catalytic activity
    		•  0.673946834085468 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.481715990485843 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.450699332958421 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.41304985993342 bayes_pls_golite062009
  • receptor activity
    		•  0.410629036454271 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.38249298672027 bayes_pls_golite062009
  • signal transducer activity
    		•  0.151379538173622 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.151379538173622 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.148194101970458 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.0031825456963297 bayes_pls_golite062009
    2
    Term Confidence Notes
  • protein transporter activity
    		•  3.54751411727402 bayes_pls_golite062009
  • clathrin binding
    		•  3.06219301699422 bayes_pls_golite062009
  • transporter activity
    		•  2.3766833486706 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.12926593993985 bayes_pls_golite062009
  • binding
    		•  2.08129940242136 bayes_pls_golite062009
  • protein binding
    		•  2.0097220759196 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.2724388835449 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.04982314606251 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.440086981303253 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.260663498540354 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.256036243669218 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.234271600707329 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.225395946682209 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.186601655036333 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.183072614802483 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.182751938544977 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.109435859778099 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0728493557966827 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0641324729536009 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0615190129942244 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0475280280823402 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle