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Protein Overview: SAM3

General Information:
Name(s) found: SAM3 / YPL274W [SGD]
Description(s) found:
Found 22 descriptions.
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  • High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 587 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: S-adenosylmethionine transport [IMPLink to PubMed article]
    spermidine transport [IDALink to PubMed article][IMPLink to PubMed article]
    putrescine transport [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: putrescine transmembrane transporter activity [IDALink to PubMed article][IMPLink to PubMed article]
    S-adenosylmethionine transmembrane transporter activity [IMPLink to PubMed article][ISSLink to PubMed article]
    spermidine transmembrane transporter activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDILKRGNES DKFTKIETES TTIPNDSDRS GSLIRRMKDS FKQSNLHVIP EDLENSEQTE  60
   61 QEKIQWKLAS QPYQKVLSQR HLTMIAIGGT LGTGLFIGLG YSLASGPAAL LIGFLLVGTS 120
  121 MFCVVQSAAE LSCQFPVSGS YATHVSRFID ESVGFTVATN YALAWLISFP SELIGCALTI 180
  181 SYWNQTVNPA VWVAIFYVFI MVLNLFGVRG FAETEFALSI IKVIAIFIFI IIGIVLIAGG 240
  241 GPNSTGYIGA KYWHDPGAFA KPVFKNLCNT FVSAAFSFGG SELVLLTSTE SKNISAISRA 300
  301 AKGTFWRIAI FYITTVVIIG CLVPYNDPRL LSGSNSEDVS ASPFVIALSN TGSMGAKVSN 360
  361 FMNVVILVAV VSVCNSCVYA SSRLIQALGA SGQLPSVCSY MDRKGRPLVG IGISGAFGLL 420
  421 GFLVASKKED EVFTWLFALC SISSFFTWFC ICMSQIRFRM ALKAQGRSND EIAYKSILGV 480
  481 YGGILGCVLN ALLIAGEIYV SAAPVGSPSS AEAFFEYCLS IPIMIVVYFA HRFYRRDWKH 540
  541 FYIKRSEIDL DTGCSVENLE LFKAQKEAEE QLIASKPFYY KIYRFWC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AGP2 AGP3 BAP3 DIP5 DUR3 ERS1 GAP1 HIP1 LYP1 MMP1 MUP1 PET8 SAM3 TAT1 TAT2 TPO3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run LST8 No Comments Reinke A, et al. (2004)
    View Run TOR2 No Comments Reinke A, et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SAM3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..56] deduced N/A No confident structure predictions are available.
    2 View Details [57..587] Pfam 172.251812 Amino acid permease No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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