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Protein Overview: MUP1

General Information:
Name(s) found: MUP1 / YGR055W [SGD]
Description(s) found:
Found 29 descriptions.
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  • High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISSLink to PubMed article]
    Biological Process: sulfur amino acid transport [IMPLink to PubMed article]
    Molecular Function: L-methionine secondary active transmembrane transporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGRTFLSQ LNVFNKENYQ FSSSTTKKEV SNSTVDADNG ASDFEAGQQF ATELDQGEKQ  60
   61 LGILSCIGLI CNRMLGTGVF AVSSTIYTLC GSVGLALIMW AVGAIIAISG LYVYMEFGTA 120
  121 IPKNGGEKNY LEAIFRKPKF FITCMYAAYI FFLGWAAGNS INTAIMFLTA ADTEVTKWNQ 180
  181 RGIGVAVVFF AFLINSLNVK IGLYLQNILG IFKIGIVLFI SITGWVALGG GLKDGYQSHN 240
  241 FRNAFEGTET ATAYGIVNAL YSVIWSFVGY SNVNYALGEV KNPVRTLKIA GPTSMVFLAI 300
  301 IYIFVNIAYF AVVPKDKLIS SKLILAADFF DIVFGGQAKR AAAALVGLSA LGNVLSVIFS 360
  361 QGRIIQQLGR EGVLPFSNFF ASSKPFNSPM VGLFQHFIVC TVTILAPPPG DAYLLVQNLI 420
  421 SYPMNIINFA ISAGLLWIYW QRRQGKIEWN PPIKAGVFVT GFFTLSNLYL IIAPYVPPSN 480
  481 GESVYSSMPY WIHCVIAWGI FFFGGVYYVV WAQLLPRWGH YKLVSKDVLG EDGFWRVKIA 540
  541 KVYDDTIGDV DTQEDGVIET NIIEHYKSEQ EKSL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AGP2 ERS1 GAP1 LYP1 MMP1 MUP1 PET8 SAM3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MUP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..52] deduced N/A No confident structure predictions are available.
    2 View Details [53..574] Pfam 3.886057 Amino acid permease No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle