Protein Overview: PET8

General Information:
Name(s) found:	PET8 / YNL003C [SGD]
Description(s) found: Found 32 descriptions. SHOW ALL	S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth [SGD]
Organism:	Saccharomyces cerevisiae
Length:	284 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA ] mitochondrial inner membrane [ISS]
Biological Process:	S-adenosylmethionine transport [IDA][IGI][IMP]
Molecular Function:	S-adenosylmethionine transmembrane transporter activity [IDA][IGI][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTFFLSLLS GAAAGTSTDL VFFPIDTIKT RLQAKGGFFA NGGYKGIYRG LGSAVVASAP  60
   61 GASLFFISYD YMKVKSRPYI SKLYSQGSEQ LIDTTTHMLS SSIGEICACL VRVPAEVVKQ 120
  121 RTQVHSTNSS WQTLQSILRN DNKEGLRKNL YRGWSTTIMR EIPFTCIQFP LYEYLKKTWA 180
  181 KANGQSQVEP WKGAICGSIA GGIAAATTTP LDFLKTRLML NKTTASLGSV IIRIYREEGP 240
  241 AVFFSGVGPR TMWISAGGAI FLGMYETVHS LLSKSFPTAG EMRA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		AGP2 MUP1 ORT1 PET8 SAM3 SFC1 YIA6

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#02 Alpha Factor Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SPT21	PET8	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	PET8	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..284]	ORFEUS	7.82	Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2