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Protein Overview: YIA6

General Information:
Name(s) found: YIA6 / YIL006W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 373 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [ISSLink to PubMed article]
    Biological Process: NAD transport [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    mitochondrial pyruvate transport [IDALink to PubMed article][IMPLink to PubMed article]
    transport [ISSLink to PubMed article]
    Molecular Function: pyruvate secondary active transmembrane transporter activity [IDALink to PubMed article][IMPLink to PubMed article]
    NAD transporter activity [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    transporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQTDNPVPN CGLLPEQQYC SADHEEPLLL HEEQLIFPDH SSQLSSADII EPIKMNSSTE  60
   61 SIIGTTLRKK WVPLSSTQIT ALSGAFAGFL SGVAVCPLDV AKTRLQAQGL QTRFENPYYR 120
  121 GIMGTLSTIV RDEGPRGLYK GLVPIVLGYF PTWMIYFSVY EFSKKFFHGI FPQFDFVAQS 180
  181 CAAITAGAAS TTLTNPIWVV KTRLMLQSNL GEHPTHYKGT FDAFRKLFYQ EGFKALYAGL 240
  241 VPSLLGLFHV AIHFPIYEDL KVRFHCYSRE NNTNSINLQR LIMASSVSKM IASAVTYPHE 300
  301 ILRTRMQLKS DIPDSIQRRL FPLIKATYAQ EGLKGFYSGF TTNLVRTIPA SAITLVSFEY 360
  361 FRNRLENIST MVI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) BPT1 LEU5 PET8 YEA6 YIA6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] deduced N/A No confident structure predictions are available.
    2 View Details [73..373] ORFEUS 7.55 Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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