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Protein Overview: YPL150W

General Information:
Name(s) found: YPL150W [SGD]
Description(s) found:
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  • gi|74676537|sp|Q12152.1|YP150_YEAST RecName: Full=Putative serine/threonine-protein kinase YPL150W [NCBI NR]
  • gi|6325107|ref|NP_015175.1| Putative protein kinase of unknown cellular role; Ypl150wp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S65161 hypothetical protein YPL150w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1403559|emb|CAA65571.1| P2597 protein [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1370320|emb|CAA97855.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Putative serine/threonine-protein kinase YPL150W OS=Saccharomyces cerevisiae GN=YPL150W PE=1 SV=1 [Swiss-Prot]
  • Putative ser/thr protein kinase [mips]
  • Putative protein kinase of unknown cellular role [SGD]
  • >Q12152 (Q12152) P2597 protein (YPL150W) [4932.FASTACCERV.txt]
  • Chr XVI from 268187-270892 [hmr_yeast5_DM3-1_pombe.fasta]
  • YPL150W, Chr XVI from 268187-270892 [yeast_orfs2]
  • YPL150W SGDID:S0006071, Chr XVI from 268187-270892, Uncharacterized ORF [yeastflysequest.fasta]
  • Ypl150wp [Saccharomyces cerevisiae]gi|1403559|emb|CAA65571.1| P2597 protein [Saccharomyces cerevisiae]gi|1370320|emb|CAA97855.1| unnamed protein product [Saccharomyces cerevisiae]gi|2132208|pir||S65161 hypothetical protein YPL150w - yeast (Saccharomyce [nrdb_11152004_Chlamydomonas]
  • (Q12152) P2597 protein (S.cerevisiae chromosome XVI reading frame ORF YPL150w) [cerv4932.FASTAC]
  • YPL150W SGDID:S000006071, Chr XVI from 268187-270892, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YPL150W SGDID:S000006071, Chr XVI from 268187-270892, Uncharacterized ORF, "Putative protein kinase of unknown cellular role" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Putative serine/threonine-protein kinase YPL150W [nr-271106-contam.fasta]
  • P2597 protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • hypothetical protein; Ypl150wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Putative serine/threonine-protein kinase YPL150W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPL150W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YPL150W SGDID:S000006071, Chr XVI from 268188-270893, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study" [yeast-030211-contam.fasta]
  • YPL150W SGDID:S000006071, Chr XVI from 268188-270893, Genome Release 64-2-1, Uncharacterized ORF, "Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study" [20141208_orf_trans.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 901 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: protein kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNPVGSSKL EQNNIKSIIG SSYNRLYSQF TSDELTEVGN YKILKQIGEG SFGKVYLALH  60
   61 RPTHRKVCLK TSDKNDPNIV REVFYHRQFD FPYITKLYEV IVTESKVWMA LEYCPGKELY 120
  121 DHLLSLRRIS LLECGELFAQ ISGAVYYAHS MHCVHRDLKL ENILLDKNGN AKLTDFGFTR 180
  181 ECMTKTTLET VCGTTVYMAP ELIERRTYDG FKIDIWSLGV ILYTLITGYL PFDDDDEAKT 240
  241 KWKIVNEEPK YDAKVIPDDA RDLISRLLAK NPGERPSLSQ VLRHPFLQPY GSVVLDQTQK 300
  301 ILCRQRSGGT QFKSKLERRL LKRLKQSGVD TQAIKQSILK KKCDSLSGLW LLLLAQGKKQ 360
  361 ENCKYPKRSR SVLSVKKVIE SATHNDTNGI SEDVLKPSLE LSRAASLSKM LNKGSDFVTS 420
  421 MTPVSRKKSK DSAKVLNPTL SKISSQRAYS HSIAGSPRKS NNFLQKVSSF FKSKKSSNSN 480
  481 SNNSIHTNVS ESLIASNRGA PSSGSFLKKN SGSIQKSRTD TVANPSRTES IGSLNENVAG 540
  541 AIVPRSANNT TLENKKTSGN EIGLKVAPEL LLNEHIRIEE PRLKRFKSSI SSEISQTSTG 600
  601 NYDSESAENS RSISFDGKVS PPPIRNRPLS EISQISNDTY ISEYSTDGNN SSFKISDTIK 660
  661 PSYIRKGSET TSQYSASSEK MTNGYGRKFV RRDLSIVSTA SSTSERSSRT DSFYDITTAT 720
  721 PVVTTDNRRN KNNNLKESVL PRFGTQRPWT GKRTYTTSRH GKNARRSSKR GLFKITSSNT 780
  781 DSIIQEVSSS EEEDHNVIYS KGKGLPTPVL QTKGLIENGL NERDEEGDDE YAIHTDGEFS 840
  841 IKPQFSDDVI DKQNHLPSVK AVATKRSLSE GSNWSSSYLD SDNNRRRVSS LLVEDGGNPT 900
  901 A

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ASE1 RPS25B STM1 VTS1 YPL150W
    View Details Ho Y, et al. (2002) ARO4 CAR2 LSP1 NAP1 OYE2 PIL1 YPL150W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3829 - low filter Green EM, et al (2005)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YPL150W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80]
    [98..111]    		 PSI-BLAST 447.228787 Pkb kinase
    2 View Details [81..97]
    [112..422]    		 PSI-BLAST 447.228787 Pkb kinase
    3 View Details [423..901] deduced N/A No confident structure predictions are available.
    4 View Details [671..727] PSI-BLAST 26.69897 Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
    5 View Details [728..901] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein kinase activity
    		•  4.05475891009228 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.7974128326421 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.59230737331367 bayes_pls_golite062009
  • kinase activity
    		•  3.41737435609334 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.2342722637405 bayes_pls_golite062009
  • binding
    		•  2.41732321506551 bayes_pls_golite062009
  • transferase activity
    		•  2.04713540681686 bayes_pls_golite062009
  • ATP binding
    		•  1.44435058039859 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.41005152726625 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.38971642420542 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.16863558166547 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.16859376715941 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.15633908642115 bayes_pls_golite062009
  • nucleotide binding
    		•  1.14964488472581 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • protein binding
    		•  0.704339182896017 bayes_pls_golite062009
  • AMP-activated protein kinase activity
    		•  0.496765880715405 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.439688030503848 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle