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Protein Overview: YPL141C

General Information:
Name(s) found: YPL141C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL141C is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 865 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: protein kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYTNKRHTY YGGFTNDLSD TFQYPQRTDE QRRKHVTFGP YILGSTLGEG EFGKVKLGWP  60
   61 KNFSNSSNST FDFPKQVAIK LIKRDSISND YRKEVKIYRE INALKHLSHP NIVKLEEVLQ 120
  121 NSRYIGIVLE YACGGEFYKY IQKKRRLKEM NACRLFSQLI SGVHYIHSKG LVHRDLKLEN 180
  181 LLLDKNENLV ITDFGFVNEF CSRNELMKTS CGSPCYAAPE LVISAEPYEA RKADIWSCGV 240
  241 ILYAILAGYL PWDDDPNNPE GSDIGRLYNY INSTPLKFPD YILPIPRDLL RRMLVSDPKK 300
  301 RINLKQIKKH EWLKPHSSFL SITPDEWDKL NNTQSVFRLA KPRRRYGSRP QSSCSTSSLG 360
  361 SRSDKRDSLV IDSTLITFPA PPQESQNHII TRPASIASDQ RLSPIRRSNR HNRSNSAASV 420
  421 ALQAVVNADR EYVLSHEQSL SPVQNIRQTT GNMTASLSPP PAISPGDIII ETTPIKRNTI 480
  481 SGSSIVPSLE EESSTTMQTS KIQPNNMASS QNHQYNKNKT QNSLQSAKNF YRTSSSSHTK 540
  541 PRPTSYHPGS YTTPPYNSNT LSIYEINEKA KSSASSQTLN QRDTSPFDST PYLALDTCIT 600
  601 SSSSIESSPK LITHGQFSVA KPSVDLQSVS GDLIKYKRDA DVVTRIYDEK YKQKRKSLRY 660
  661 SGIFSDISCD TVTEESDELR PPESPLQQHE GQESIDKAKT EDTSEKGSKS SNIAKATAQK 720
  721 HVNNHLERSL NEAESTKKRF SFLSLYSYDT SKSSLYSSMD SKRKPSPPSQ RRPKKDDSYQ 780
  781 TNSKNHYITA SNMQTSHQVS KDLPAPTMVQ NKCTLETKKA VRSNRSSIMV SEVNKASVDN 840
  841 KAAQSPEHST AKRVLGFFKR RSMKI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) SAG1 TRL1 YJR124C YPL141C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YPL141C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99]
    [116..130]    		 PSI-BLAST 450.264245 Cell cycle checkpoint kinase chk1
    2 View Details [100..115]
    [131..140]
    [156..205]    		 PSI-BLAST 450.264245 Cell cycle checkpoint kinase chk1
    3 View Details [141..155]
    [206..370]    		 PSI-BLAST 450.264245 Cell cycle checkpoint kinase chk1
    4 View Details [371..865] deduced N/A No confident structure predictions are available.
    5 View Details [774..865] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein kinase activity
    		•  4.05475891009228 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  4.04751809021925 bayes_pls_golite062009
  • kinase activity
    		•  3.88704262604357 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.7974128326421 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.55786569314106 bayes_pls_golite062009
  • transferase activity
    		•  2.750643926194 bayes_pls_golite062009
  • binding
    		•  2.41732321506551 bayes_pls_golite062009
  • protein binding
    		•  1.75479345161448 bayes_pls_golite062009
  • ATP binding
    		•  1.44435058039859 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.41005152726625 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.38971642420542 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.16863558166547 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.16859376715941 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.15633908642115 bayes_pls_golite062009
  • nucleotide binding
    		•  1.14964488472581 bayes_pls_golite062009
  • AMP-activated protein kinase activity
    		•  1.12923456567012 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.439688030503848 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle