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Protein Overview: SAG1

General Information:
Name(s) found: SAG1 / YJR004C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 650 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article]
    Biological Process: agglutination involved in conjugation with cellular fusion [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: cell adhesion molecule binding [IMPLink to PubMed articleLink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTFLKIILW LFSLALASAI NINDITFSNL EITPLTANKQ PDQGWTATFD FSIADASSIR  60
   61 EGDEFTLSMP HVYRIKLLNS SQTATISLAD GTEAFKCYVS QQAAYLYENT TFTCTAQNDL 120
  121 SSYNTIDGSI TFSLNFSDGG SSYEYELENA KFFKSGPMLV KLGNQMSDVV NFDPAAFTEN 180
  181 VFHSGRSTGY GSFESYHLGM YCPNGYFLGG TEKIDYDSSN NNVDLDCSSV QVYSSNDFND 240
  241 WWFPQSYNDT NADVTCFGSN LWITLDEKLY DGEMLWVNAL QSLPANVNTI DHALEFQYTC 300
  301 LDTIANTTYA TQFSTTREFI VYQGRNLGTA SAKSSFISTT TTDLTSINTS AYSTGSISTV 360
  361 ETGNRTTSEV ISHVVTTSTK LSPTATTSLT IAQTSIYSTD SNITVGTDIH TTSEVISDVE 420
  421 TISRETASTV VAAPTSTTGW TGAMNTYISQ FTSSSFATIN STPIISSSAV FETSDASIVN 480
  481 VHTENITNTA AVPSEEPTFV NATRNSLNSF CSSKQPSSPS SYTSSPLVSS LSVSKTLLST 540
  541 SFTPSVPTSN TYIKTKNTGY FEHTALTTSS VGLNSFSETA VSSQGTKIDT FLVSSLIAYP 600
  601 SSASGSQLSG IQQNFTSTSL MISTYEGKAS IFFSAELGSI IFLLLSYLLF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) SAG1 TRL1 YJR124C YPL141C
    View Details Qiu et al. (2008) AGA1 AGA2 SAG1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..369] ORFEUS 10.54 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    2 View Details [370..461] ORFEUS 10.54 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    3 View Details [462..650] ORFEUS 12.88 Sec24


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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