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Protein Overview: AGA1

General Information:
Name(s) found: AGA1 / YNR044W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 725 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed articleLink to PubMed article]
    Biological Process: agglutination involved in conjugation with cellular fusion [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: cell adhesion molecule binding [IMPLink to PubMed articleLink to PubMed article][ISSLink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLSFAHFTY LFTILLGLTN IALASDPETI LVTITKTNDA NGVVTTTVSP ALVSTSTIVQ  60
   61 AGTTTLYTTW CPLTVSTSSA AEISPSISYA TTLSRFSTLT LSTEVCSHEA CPSSSTLPTT 120
  121 TLSVTSKFTS YICPTCHTTA ISSLSEVGTT TVVSSSAIEP SSASIISPVT STLSSTTSSN 180
  181 PTTTSLSSTS TSPSSTSTSP SSTSTSSSST STSSSSTSTS SSSTSTSPSS TSTSSSLTST 240
  241 SSSSTSTSQS STSTSSSSTS TSPSSTSTSS SSTSTSPSSK STSASSTSTS SYSTSTSPSL 300
  301 TSSSPTLAST SPSSTSISST FTDSTSSLGS SIASSSTSVS LYSPSTPVYS VPSTSSNVAT 360
  361 PSMTSSTVET TVSSQSSSEY ITKSSISTTI PSFSMSTYFT TVSGVTTMYT TWCPYSSESE 420
  421 TSTLTSMHET VTTDATVCTH ESCMPSQTTS LITSSIKMST KNVATSVSTS TVESSYACST 480
  481 CAETSHSYSS VQTASSSSVT QQTTSTKSWV SSMTTSDEDF NKHATGKYHV TSSGTSTIST 540
  541 SVSEATSTSS IDSESQEQSS HLLSTSVLSS SSLSATLSSD STILLFSSVS SLSVEQSPVT 600
  601 TLQISSTSEI LQPTSSTAIA TISASTSSLS ATSISTPSTS VESTIESSSL TPTVSSIFLS 660
  661 SSSAPSSLQT SVTTTEVSTT SISIQYQTSS MVTISQYMGS GSQTRLPLGK LVFAIMAVAC 720
  721 NVIFS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AGA1 SAG1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data AGA1 Huh WK, et al. (2003)
    View Data AGA1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] MSA 3.154991 View MSA. No confident structure predictions are available.
    2 View Details [170..243] ab initio 14.39 No description for 1m2vB was found.
    3 View Details [244..319] deduced N/A No confident structure predictions are available.
    4 View Details [320..453] MSA 2.166997 View MSA. No confident structure predictions are available.
    5 View Details [454..602] ab initio 11.45 No description for 1deqA was found.
    6 View Details [603..725] MSA 1.121992 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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