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Protein Overview: YPL088W

General Information:
Name(s) found: YPL088W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 342 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: cellular aldehyde metabolic process [ISSLink to PubMed article]
    Molecular Function: aryl-alcohol dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLVKQVRLG NSGLKISPIV IGCMSYGSKK WADWVIEDKT QIFKIMKHCY DKGLRTFDTA  60
   61 DFYSNGLSER IIKEFLEYYS IKRETVVIMT KIYFPVDETL DLHHNFTLNE FEELDLSNQR 120
  121 GLSRKHIIAG VENSVKRLGT YIDLLQIHRL DHETPMKEIM KALNDVVEAG HVRYIGASSM 180
  181 LATEFAELQF TADKYGWFQF ISSQSYYNLL YREDERELIP FAKRHNIGLL PWSPNARGML 240
  241 TRPLNQSTDR IKSDPTFKSL HLDNLEEEQK EIINRVEKVS KDKKVSMAML SIAWVLHKGC 300
  301 HPIVGLNTTA RVDEAIAALQ VTLTEEEIKY LEEPYKPQRQ RC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239]
    [285..324]    		 PSI-BLAST 327.383689 Voltage-dependent K+ channel beta subunit
    2 View Details [240..284]
    [325..342]    		 PSI-BLAST 327.383689 Voltage-dependent K+ channel beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • potassium channel activity
    		•  7.51963276589303 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  7.40239094355354 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  6.67507110634301 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  6.588881463055 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.52286930358188 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.50716590143831 bayes_pls_golite062009
  • cation channel activity
    		•  5.72172645555113 bayes_pls_golite062009
  • ion channel activity
    		•  5.15119282480682 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  5.07214658557001 bayes_pls_golite062009
  • channel activity
    		•  5.07214658557001 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  5.02503292701043 bayes_pls_golite062009
  • gated channel activity
    		•  4.92848832197692 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.33866876957213 bayes_pls_golite062009
  • pyridoxine 4-dehydrogenase activity
    		•  3.25535446462297 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.72342789448248 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.63772951680109 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.62743427046359 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.58068601897668 bayes_pls_golite062009
  • aldo-keto reductase activity
    		•  2.57303336304449 bayes_pls_golite062009
  • aryl-alcohol dehydrogenase activity
    		•  2.5168190536972 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.46488926936937 bayes_pls_golite062009
  • catalytic activity
    		•  1.68179794468736 bayes_pls_golite062009
  • transporter activity
    		•  1.24767072239634 bayes_pls_golite062009
  • aldehyde reductase activity
    		•  1.16639404121425 bayes_pls_golite062009
  • binding
    		•  1.15657176144267 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.03420335553507 bayes_pls_golite062009
  • potassium channel regulator activity
    		•  1.03017249802223 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.783004917746429 bayes_pls_golite062009
  • protein binding
    		•  0.220529867719707 bayes_pls_golite062009
  • 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity
    		•  0.207008954325429 bayes_pls_golite062009
  • trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
    		•  0.207008954325429 bayes_pls_golite062009
    		• 0.139676323362391 bayes_pls_golite062009
  • channel regulator activity
    		•  0.12154513851913 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle