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Protein Overview: TRM44

General Information:
Name(s) found: TRM44 / YPL030W [SGD]
Description(s) found:
Found 26 descriptions.
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  • tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 567 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGDGSAHIS KNNQNQHKDR FKFIVNDKSI LGPQWLSLYQ TDGKVTFAKS HFEQAMMNVI  60
   61 REPNINSTVI LRADILKEIN HAAEAGSEPK FDESVLKKFE IDNGNESGEE DVKKINIEDL 120
  121 NIRSCETSES LKLSPVHEFV RRIIPRNFYK DAIINQTCLI LNSKDPNFQE TSLIVYTPHI 180
  181 NSEKDCPFYI PRTQSVGILL HQSVLSVHYI PFPEDKTAFT DESERVVRTA YRLLQTANKH 240
  241 SKGVMQGYEK RVNHDQVVNK VNFQNTYIVL KKKYSKFLVE NWAESTDPKK HVFEDIAIAA 300
  301 FLIELWIKVY GPDFRSKMQF RDLGCGNGAL CYILLSESIK GLGIDARKRK SWSIYPPEVQ 360
  361 SSLKEQVIIP SILLRPHPAL KRQVPHLEHN GRFFPVKVTH EVIAPATVVY SSEDLLKSPQ 420
  421 VNTAEFPPDT FIIGNHSDEL TCWIPLLGHP YMVIPCCSHN FSGQRVRFNV RKRSPRSNEI 480
  481 KNQNNSKSTY SGLVDHVEYI SSRVGWKVEK EMLRIPSTRN AAIIGVENAT LKHFPTQAVY 540
  541 DMIWEDGGAE GWIQNTMSLL KRNPRNH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CAB3 No Comments Hazbun TR, et al. (2003)
    View Run PAN1 No Comments Toshima J, et al (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TRM44 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..165] deduced N/A No confident structure predictions are available.
    2 View Details [166..567] MSA 4.01292 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle