YRC Public Data Repository - Protein Structure Prediction

Protein:	TRM44
Organism:	Saccharomyces cerevisiae
Length:	567 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRM44.

Description	E-value	Query Range	Subject Range
TRM44 - tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(C... TRM44_YEAST - tRNA (uracil-O(2)-)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TR...	0.0	[1..567]	[1..567]
SPCC663.10 - methyltransferase, DUF1613 family TRM44_SCHPO - tRNA (uracil-O(2)-)-methyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=trm4...	0.0	[34..567]	[31..502]
TRM44_NEUCR - tRNA (uracil-O(2)-)-methyltransferase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708... TRM44_NEUCR, U38... - Putative methyltransferase UPF0383 OS=Neurospora crassa GN=B13D15.160 PE=3 SV=1, tRNA (uracil-O(2)-)...	0.0	[33..561]	[37..507]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[178..526]	[127..404]
TRM44_MOUSE, U38... - Putative methyltransferase UPF0383 OS=Mus musculus PE=2 SV=1, Probable tRNA (uracil-O(2)-)-methyltra...	3.0E-88	[254..528]	[249..462]
gi\|23272859 - gi\|23272859\|gb\|AAH35655.1\| C4orf23 protein [Homo sapiens]	7.0E-88	[233..528]	[33..265]
gi\|27694979 - gi\|27694979\|gb\|AAH43909.1\| LOC398534 protein [Xenopus laevis]	1.0E-84	[233..528]	[188..420]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGDGSAHIS KNNQNQHKDR FKFIVNDKSI LGPQWLSLYQ TDGKVTFAKS HFEQAMMNVI  60
   61 REPNINSTVI LRADILKEIN HAAEAGSEPK FDESVLKKFE IDNGNESGEE DVKKINIEDL 120
  121 NIRSCETSES LKLSPVHEFV RRIIPRNFYK DAIINQTCLI LNSKD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [166-567]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNFQETSLIV YTPHINSEKD CPFYIPRTQS VGILLHQSVL SVHYIPFPED KTAFTDESER  60
   61 VVRTAYRLLQ TANKHSKGVM QGYEKRVNHD QVVNKVNFQN TYIVLKKKYS KFLVENWAES 120
  121 TDPKKHVFED IAIAAFLIEL WIKVYGPDFR SKMQFRDLGC GNGALCYILL SESIKGLGID 180
  181 ARKRKSWSIY PPEVQSSLKE QVIIPSILLR PHPALKRQVP HLEHNGRFFP VKVTHEVIAP 240
  241 ATVVYSSEDL LKSPQVNTAE FPPDTFIIGN HSDELTCWIP LLGHPYMVIP CCSHNFSGQR 300
  301 VRFNVRKRSP RSNEIKNQNN SKSTYSGLVD HVEYISSRVG WKVEKEMLRI PSTRNAAIIG 360
  361 VENATLKHFP TQAVYDMIWE DGGAEGWIQN TMSLLKRNPR NH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits