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Protein Overview: TSR3

General Information:
Name(s) found: TSR3 / YOR006C [SGD]
Description(s) found:
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  • gi|6324579|ref|NP_014648.1| Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; Null mutant accumulates 20S pre-rRNA; Tsr3p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|2833220|sp|Q12094.1|YO006_YEAST RecName: Full=UPF0293 protein YOR006C [NCBI NR]
  • pir||S61990 hypothetical protein YOR006c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420098|emb|CAA99194.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1151002|gb|AAC49486.1| hypothetical protein UND313 [NCBI NR]
  • (Q12094) Hypothetical UPF0293 protein YOR006c [Swiss-Prot]
  • UPF0293 protein YOR006C OS=Saccharomyces cerevisiae GN=YOR006C PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function localised to cytoplasm and nucleus [mips]
  • Protein required for correct processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus [SGD]
  • (Q12094) Hypothetical UPF0293 protein YOR006C [4932.FASTACCERV.txt]
  • Chr XV from 338621-337680, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 337680-338621, reverse complement [yeastorf3.fasta]
  • YOR006C, Chr XV from 337680-338621, reverse complement [yeast_orfs2]
  • YOR006C SGDID:S0005532, Chr XV from 338621-337680, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Yor006cp [Saccharomyces cerevisiae]gi|1420098|emb|CAA99194.1| unnamed protein product [Saccharomyces cerevisiae]gi|2833220|sp|Q12094|YO06_YEAST Hypothetical UPF0293 protein YOR006Cgi|2132030|pir||S61990 hypothetical protein YOR006c - yeast (Saccharomyc [nrdb_11152004_Chlamydomonas]
  • YOR006C SGDID:S000005532, Chr XV from 338621-337680, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YOR006C SGDID:S000005532, Chr XV from 338622-337681, reverse complement, Uncharacterized ORF, "Hypothetical protein" [yeast-contam.fasta]
  • YOR006C SGDID:S000005532, Chr XV from 338622-337681, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; Null mutant accumulates 20 [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • YOR006C SGDID:S000005532, Chr XV from 338622-337681, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" [yeast-200209-contam.fasta]
  • UPF0293 protein YOR006C [nr-271106-contam.fasta]
  • hypothetical protein UND313 [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • hypothetical protein; Yor006cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • TSR3 SGDID:S000005532, Chr XV from 338622-337681, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta]
  • [chemostatdb.fasta]
  • TSR3 SGDID:S000005532, Chr XV from 338621-337680, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for correct processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" [yeast-030211-contam.fasta]
  • TSR3 SGDID:S000005532, Chr XV from 338621-337680, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein required for 20S pre-rRNA processing; involved in processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; relative distribution to the nucleus increases upon DNA replication stress" [20141208_orf_trans.fasta]
  • YOR006C SGDID:S000005532, Chr XV from 338621-337680, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for correct processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 313 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKGKNKMHE PKNGRPQRGA NGHSSRQNHR RMEMKYDNSE KMKFPVKLAM WDFDHCDPKR  60
   61 CSGKKLERLG LIKSLRVGQK FQGIVVSPNG KGVVCPDDLE IVEQHGASVV ECSWARLEEV 120
  121 PFNKIGGKHE RLLPYLVAAN QVNYGRPWRL NCVEALAACF AIVGRMDWAS ELLSHFSWGM 180
  181 GFLELNKELL EIYQQCTDCD SVKRAEEEWL QKLEKETQER KSRAKEEDIW MMGNINRRGN 240
  241 GSQSDTSESE ENSEQSDLEG NNQCIEYDSL GNAIRIDNMK SREAQSEESE DEESGSKENG 300
  301 EPLSYDPLGN LIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TSR3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] MSA 8.018944 View MSA. No confident structure predictions are available.
    2 View Details [239..313] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle