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Protein Overview: PDR17

General Information:
Name(s) found: PDR17 / YNL264C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 350 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: response to drug [IGILink to PubMed article]
    phospholipid biosynthetic process [IMPLink to PubMed article]
    phospholipid transport [IDALink to PubMed article]
    Molecular Function: phosphatidylinositol transporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLFSRKRDH TPAVPKEKLI PCDKIFLDPP AKYGNAPLLE PISEDQNEKY RAVLRHFQDD  60
   61 DLKLPENLND LDNGTHANDR PLSDWEKFWL SRECFLRYLR ANKWNTANAI KGLTKTLVWR 120
  121 REIGLTHGKE DKDPLTADKV AVENETGKQV ILGFDNAKRP LYYMKNGRQN TESSFRQVQE 180
  181 LVYMMETATT VAPQGVEKIT VLVDFKSYKE PGIITDKAPP ISIARMCLNV MQDHYPERLA 240
  241 KCVLINIPWF AWAFLKMMYP FLDPATKAKA IFDEPFENHI EPSQLDALYN GLLDFKYKHE 300
  301 VYWPDMVKKV DDLRLKRFDR FLKFGGIVGL SEYDTKGQHD ELKYPVDMVI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) PDR17 PSD2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PDR17 YPL272C 2 Unpublished Fields Lab Data
    View Screen PDR17 FUN30 1 Unpublished Fields Lab Data
    View Screen PDR17 ATP1 1 Unpublished Fields Lab Data
    View Screen PDR17 QDR3 1 Unpublished Fields Lab Data
    View Screen PDR17 RXT3 1 Unpublished Fields Lab Data
    View Screen PDR17 WWM1 1 Unpublished Fields Lab Data
    View Screen PDR17 YIL171W 1 Unpublished Fields Lab Data
    View Screen PDR17 PPZ1 1 Unpublished Fields Lab Data
    View Screen PDR17 CUS1 1 Unpublished Fields Lab Data
    View Screen PDR17 GPM3 1 Unpublished Fields Lab Data
    View Screen PDR17 RSA1 1 Unpublished Fields Lab Data
    View Screen MLC1 PDR17 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PDR17 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] PSI-BLAST 113.68867 N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
    2 View Details [118..350] PSI-BLAST 113.68867 N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phospholipid transporter activity
    		•  4.82372291869245 bayes_pls_golite062009
  • lipid transporter activity
    		•  3.44932625048477 bayes_pls_golite062009
  • phosphatidylinositol transporter activity
    		•  3.08477039249457 bayes_pls_golite062009
  • binding
    		•  1.41701101210975 bayes_pls_golite062009
  • transporter activity
    		•  1.00447017621654 bayes_pls_golite062009
  • vitamin binding
    		•  0.87942237566918 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.658164745879483 bayes_pls_golite062009
  • vitamin E binding
    		•  0.425230876259729 bayes_pls_golite062009
  • protein binding
    		•  0.132818074687599 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle