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Protein Overview: QDR3

General Information:
Name(s) found: QDR3 / YBR043C [SGD]
Description(s) found:
Found 22 descriptions.
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  • Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 689 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISSLink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: drug transmembrane transport [IMPLink to PubMed article]
    Molecular Function: drug transmembrane transporter activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAQGSQSNV GSLRSNCSDN SLPNNHVMMH CDESSGTPHS EHNDYSYEKT NLESTASNSR  60
   61 EHRDNQLSRL KSEEYVVPKN QRRGLLPQLA IIPEFKDARD YPPMMKKMIV FLIAFSSMMG 120
  121 PMGTSIIFPA INSITTEFKT SVIMVNVSIG VYLLSLGVFP LWWSSLSELE GRRTTYITSF 180
  181 ALLFAFNIGS ALAPDINSFI ALRMLCGAAS ASVQSVGAGT VADLYISEDR GKNLSYYYLG 240
  241 PLLAPLLSPI FGSLLVNRWP WRSTQWFMVI LSGCNVILLT VLLPETLRKQ DSKGAIAQIL 300
  301 AERRIQVDNN ERGEIQEDYQ RGEDETDRIE NQVATLSTEK HNYVGEVRDQ DSLDLESHSS 360
  361 PNTYDGRAGE TQLQRIYTEA SRSLYEYQLD DSGIDATTAQ VTRIRSTDPK LARSIRENSL 420
  421 RKLQTNLEEQ VKKVLSSNGG EIAPKQVSAV RKVWDTFFVY FIKPLKSLHF LEYPPVALAI 480
  481 TFSAISFSTV YFVNMTVEYK YSRPPYNFKP LYIGLLYIPN SVTYFFASIY GGRWVDMLLK 540
  541 RYKEKYGILA PEARISWNVV TSVISFPIAL LIFGWCLDKK CHWVTPLIGT ALFGYAAMMT 600
  601 IGATLSYLVD SLPGKGATGV ALNNLIRQIL AATAVFVTTP MLNGMGTGWA FTMLAFIVLG 660
  661 ASSVLIILKK HGDYWRENYD LQKLYDKID

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AQR1 ATR1 FLR1 QDR1 QDR2 QDR3 SGE1 SNQ2 YHK8

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data QDR3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] deduced N/A No confident structure predictions are available.
    2 View Details [71..281]
    [323..547]    		 PSI-BLAST 4.30103 No description for 1ja5A_ was found.
    3 View Details [282..322] PSI-BLAST 4.30103 No description for 1ja5A_ was found.
    4 View Details [548..689] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle