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Protein Overview: QDR1

General Information:
Name(s) found: QDR1 / YIL120W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ketoconazole, fluconazole, and barban [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 563 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISSLink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: drug transmembrane transport [IMPLink to PubMed article]
    Molecular Function: drug transmembrane transporter activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKQQTSVMR NASIAKEERE GSDNNNVDRS SSDAISDNDA ERSNSHSEID NESNFDMVPY  60
   61 SRFSHKQKML LVVQCAFTGF FSTVAGSIYY PVLTIIERKF NITEELANVT IVVYFIFQGV 120
  121 APSIMGGLAD TFGRRPIVLW AILAYFCACI GLACAHNYAQ ILALRCLQAA GISPVIAINS 180
  181 GIMGDVTTKV ERGGYVGLVA GFQVVGTAFG ALIGAGLSSK WGWRAIFWFL AIGSGICLVF 240
  241 STLLMPETKR TLVGNGSVTP RSFLNRSLIL HVGSVKKTLH LDDPDPETLE PRTSVDFLAP 300
  301 LKILHIREID ILLSIAGLQF STWTTHQTAL TIVLSKKYNL SVAKIGLCFL PAGISTLTSI 360
  361 ISAGRYLNWS YRTRKVKYNR WIKEQELQLM EKYKGDKNKV AELIHSNSHY AFNLVEARLH 420
  421 PAFVTLLLSS IGFTAFGWCI SVKTPLAAVL CTSAFASLFS NCILTFSTTL IVDLFPSKAS 480
  481 TATGCLNLFR CLLSAIFIAA LTKMVEKMRY GGVFTFLSAI TSSSSLLLFY LLKNGKQLSF 540
  541 DRIRANDKSA GRSVGKNSEK VST

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AZR1 CTR3 QDR1 QDR2 QDR3 YHK8

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] MSA 2.930996 View MSA. No confident structure predictions are available.
    2 View Details [69..478] PSI-BLAST 21.045757 No description for 1lviA_ was found.
    3 View Details [479..563] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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