YRC Public Data Repository - Protein Structure Prediction

Protein:	QDR1
Organism:	Saccharomyces cerevisiae
Length:	563 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QDR1.

Description	E-value	Query Range	Subject Range
gi\|13702155, gi\|... - gi\|13702161\|dbj\|BAB43818.1\| CaNAG4 [Candida albicans], gi\|13702155\|dbj\|BAB43815.1\| CaNAG4 [Candida a... gi\|238882925 - gi\|238882925\|gb\|EEQ46563.1\| hypothetical protein CAWG_04919 [Candida albicans WO-1]	4.0E-87	[2..545]	[69..573]
YCT4_SCHPO - Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC7... SPCC794.04c - membrane transporter	2.0E-86	[3..545]	[44..544]
QDR1 - Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ke... QDR1_YEAST - Quinidine resistance protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR1 PE=1...	8.0E-84	[1..563]	[1..563]
gi\|21225257, gi\|... - gi\|7649556\|emb\|CAB89031.1\| putative membrane transport protein. [Streptomyces coelicolor A3(2)], gi\|...	2.0E-81	[48..543]	[11..524]
gi\|223644446, gi... - gi\|241956766\|ref\|XP_002421103.1\| multidrug transporter; plasma membrane transporter of the major fac... gi\|2951670 - gi\|2951670\|emb\|CAA12730.1\| multidrug transporter [Candida dubliniensis]	8.0E-80	[6..546]	[44..557]

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Predicted Domain #1

Region A:
Residues: [1-68]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKQQTSVMR NASIAKEERE GSDNNNVDRS SSDAISDNDA ERSNSHSEID NESNFDMVPY  60
   61 SRFSHKQK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [69-478]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLVVQCAFT GFFSTVAGSI YYPVLTIIER KFNITEELAN VTIVVYFIFQ GVAPSIMGGL  60
   61 ADTFGRRPIV LWAILAYFCA CIGLACAHNY AQILALRCLQ AAGISPVIAI NSGIMGDVTT 120
  121 KVERGGYVGL VAGFQVVGTA FGALIGAGLS SKWGWRAIFW FLAIGSGICL VFSTLLMPET 180
  181 KRTLVGNGSV TPRSFLNRSL ILHVGSVKKT LHLDDPDPET LEPRTSVDFL APLKILHIRE 240
  241 IDILLSIAGL QFSTWTTHQT ALTIVLSKKY NLSVAKIGLC FLPAGISTLT SIISAGRYLN 300
  301 WSYRTRKVKY NRWIKEQELQ LMEKYKGDKN KVAELIHSNS HYAFNLVEAR LHPAFVTLLL 360
  361 SSIGFTAFGW CISVKTPLAA VLCTSAFASL FSNCILTFST TLIVDLFPSK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.045757
Match:	1lviA_
Description:	No description for 1lviA_ was found.

Predicted Domain #3

Region A:
Residues: [479-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASTATGCLNL FRCLLSAIFI AALTKMVEKM RYGGVFTFLS AITSSSSLLL FYLLKNGKQL  60
   61 SFDRIRANDK SAGRSVGKNS EKVST

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits