YRC Public Data Repository - Protein Structure Prediction

Protein:	QDR3
Organism:	Saccharomyces cerevisiae
Length:	689 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QDR3.

Description	E-value	Query Range	Subject Range
QDR3 - Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ba...	0.0	[1..689]	[1..689]
gi\|21225257, gi\|... - gi\|7649556\|emb\|CAB89031.1\| putative membrane transport protein. [Streptomyces coelicolor A3(2)], gi\|...	2.0E-62	[67..593]	[1..509]
gi\|15927932, gi\|... - gi\|15927932\|ref\|NP_375465.1\| hypothetical protein SA2142 [Staphylococcus aureus subsp. aureus N315],... gi\|253314692 - gi\|253314692\|ref\|ZP_04837905.1\| hypothetical protein SauraC_00665 [Staphylococcus aureus subsp. aure... gi\|12003106, gi\|... - pir\|\|C90035 hypothetical protein SA2142 [imported] - Staphylococcus aureus (strain N315), gi\|120031... gi\|255007128 - gi\|255007128\|ref\|ZP_05145729.2\| hypothetical protein SauraM_11685 [Staphylococcus aureus subsp. aure... gi\|14248126, gi\|... - gi\|15925342\|ref\|NP_372876.1\| multidrug resistance protein [Staphylococcus aureus subsp. aureus Mu50]... gi\|269203983\|ref... - EmrB/QacA family drug resistance transporter [Staphylococcus aureus subsp. aureus ED98] gi\|90583610, gi\|... - gi\|90583610\|ref\|ZP_01239364.1\| Drug resistance transporter EmrB/QacA subfamily [Staphylococcus aureu... gi\|147741858, gi... - gi\|90585929\|ref\|ZP_01241634.1\| Drug resistance transporter EmrB/QacA subfamily [Staphylococcus aureu... gi\|156980667, gi... - gi\|156980667\|ref\|YP_001442926.1\| hypothetical protein SAHV_2336 [Staphylococcus aureus subsp. aureus...	2.0E-62	[2..397]	[44..428]
YCT4_SCHPO - Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC7... SPCC794.04c - membrane transporter	3.0E-61	[196..682]	[108..544]
gi\|5420310 - gi\|5420310\|emb\|CAB46647.1\| putative multiple drug resistance protein [Penicillium olsonii]	2.0E-60	[192..686]	[85..535]
gi\|13702155, gi\|... - gi\|13702161\|dbj\|BAB43818.1\| CaNAG4 [Candida albicans], gi\|13702155\|dbj\|BAB43815.1\| CaNAG4 [Candida a... gi\|238882925 - gi\|238882925\|gb\|EEQ46563.1\| hypothetical protein CAWG_04919 [Candida albicans WO-1]	2.0E-57	[211..682]	[142..573]

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Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAQGSQSNV GSLRSNCSDN SLPNNHVMMH CDESSGTPHS EHNDYSYEKT NLESTASNSR  60
   61 EHRDNQLSRL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [71-281]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSEEYVVPKN QRRGLLPQLA IIPEFKDARD YPPMMKKMIV FLIAFSSMMG PMGTSIIFPA  60
   61 INSITTEFKT SVIMVNVSIG VYLLSLGVFP LWWSSLSELE GRRTTYITSF ALLFAFNIGS 120
  121 ALAPDINSFI ALRMLCGAAS ASVQSVGAGT VADLYISEDR GKNLSYYYLG PLLAPLLSPI 180
  181 FGSLLVNRWP WRSTQWFMVI LSGCNVILLT V

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [323-547]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDETDRIENQ VATLSTEKHN YVGEVRDQDS LDLESHSSPN TYDGRAGETQ LQRIYTEASR  60
   61 SLYEYQLDDS GIDATTAQVT RIRSTDPKLA RSIRENSLRK LQTNLEEQVK KVLSSNGGEI 120
  121 APKQVSAVRK VWDTFFVYFI KPLKSLHFLE YPPVALAITF SAISFSTVYF VNMTVEYKYS 180
  181 RPPYNFKPLY IGLLYIPNSV TYFFASIYGG RWVDMLLKRY KEKYG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.30103
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted Domain #3

Region A:
Residues: [282-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLPETLRKQD SKGAIAQILA ERRIQVDNNE RGEIQEDYQR G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.30103
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted Domain #4

Region A:
Residues: [548-689]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILAPEARISW NVVTSVISFP IALLIFGWCL DKKCHWVTPL IGTALFGYAA MMTIGATLSY  60
   61 LVDSLPGKGA TGVALNNLIR QILAATAVFV TTPMLNGMGT GWAFTMLAFI VLGASSVLII 120
  121 LKKHGDYWRE NYDLQKLYDK ID

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits