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View Structure Prediction Details

Protein: PDR17
Organism: Saccharomyces cerevisiae
Length: 350 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDR17.

Description E-value Query
Range
Subject
Range
PDR17 - Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylc...
gi|151944283 - gi|151944283|gb|EDN62561.1| pleiotropic drug resistance protein [Saccharomyces cerevisiae YJM789]
gi|207341913 - gi|207341913|gb|EDZ69844.1| YNL264Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409234 - gi|190409234|gb|EDV12499.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
PDR17_YEAST - Phosphatidylinositol transfer protein PDR17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
2.0E-76 [1..350] [1..350]
gi|22137166, gi|... - gi|22137166|gb|AAM91428.1| AT4g39170/T22F8_70 [Arabidopsis thaliana], gi|14335006|gb|AAK59767.1| AT4...
2.0E-67 [6..328] [22..366]
YJX4_SCHPO - CRAL-TRIO domain-containing protein C23B6.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...
SPCC23B6.04c - sec14 cytosolic factor family
2.0E-65 [6..343] [546..874]
gi|14486705 - gi|14486705|gb|AAK63247.1|AF367433_1 phosphatidylinositol transfer-like protein III [Lotus japonicus...
2.0E-64 [6..310] [22..350]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-63 [6..328] [22..369]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLFSRKRDH TPAVPKEKLI PCDKIFLDPP AKYGNAPLLE PISEDQNEKY RAVLRHFQDD  60
   61 DLKLPENLND LDNGTHANDR PLSDWEKFWL SRECFLRYLR ANKWNTANAI KGLTKTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 113.68867
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 4.82372291869245 bayes_pls_golite062009
lipid transporter activity 3.44932625048477 bayes_pls_golite062009
phosphatidylinositol transporter activity 3.08477039249457 bayes_pls_golite062009
binding 1.41701101210975 bayes_pls_golite062009
transporter activity 1.00447017621654 bayes_pls_golite062009
vitamin binding 0.87942237566918 bayes_pls_golite062009
substrate-specific transporter activity 0.658164745879483 bayes_pls_golite062009
vitamin E binding 0.425230876259729 bayes_pls_golite062009
protein binding 0.132818074687599 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [118-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VWRREIGLTH GKEDKDPLTA DKVAVENETG KQVILGFDNA KRPLYYMKNG RQNTESSFRQ  60
   61 VQELVYMMET ATTVAPQGVE KITVLVDFKS YKEPGIITDK APPISIARMC LNVMQDHYPE 120
  121 RLAKCVLINI PWFAWAFLKM MYPFLDPATK AKAIFDEPFE NHIEPSQLDA LYNGLLDFKY 180
  181 KHEVYWPDMV KKVDDLRLKR FDRFLKFGGI VGLSEYDTKG QHDELKYPVD MVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 113.68867
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle