Protein Overview: YNL058C

General Information:
Name(s) found:	YNL058C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|994828\|gb\|AAA99653.1\| Ynl2433p [NCBI NR] gi\|6324271\|ref\|NP_014340.1\| Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene; Ynl058cp [Saccharomyces cerevisiae] [NCBI NR] gi\|51012923\|gb\|AAT92755.1\| YNL058C [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S58719 probable membrane protein YNL058c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1730737\|sp\|P53947.1\|YNF8_YEAST RecName: Full=Uncharacterized protein YNL058C [NCBI NR] gi\|1301929\|emb\|CAA95932.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein YNL058C OS=Saccharomyces cerevisiae GN=YNL058C PE=1 SV=1 [Swiss-Prot] Protein of unknown function localised to vacuole [mips] Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene [SGD] YNL058C, Chr XIV from 515759-516709, reverse complement [yeast_orfs2] Chr XIV from 515759-516709, reverse complement [yeastorf3.fasta] Chr XIV from 516709-515759, reverse complement [yeastorf5.fasta] (P53947) Hypothetical 35.0 kDa protein in ARP5-OMP2 intergenic region [4932.FASTACCERV.txt] YNL058C SGDID:S0005003, Chr XIV from 516711-515761, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] YNL058C SGDID:S0005003, Chr XIV from 516712-515762, reverse complement, Uncharacterized ORF [10112005cervSGD.fasta] Protein of unknown function, localizes to the vacuole; potential Cdc28p substrate [Saccharomyces cerevisiae]gi\|51012923\|gb\|AAT92755.1\| YNL058C [Saccharomyces cerevisiae]gi\|1301929\|emb\|CAA95932.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|213 [nrdb_11152004_Chlamydomonas] YNL058C SGDID:S000005003, Chr XIV from 516714-515764, reverse complement, Uncharacterized ORF, "Protein of unknown function, localizes to the vacuole; potential Cdc28p substrate" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YNL058C SGDID:S000005003, Chr XIV from 516714-515764, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene" [yeast-contam.fasta] Hypothetical 35.0 kDa protein in ARP5-OMP2 intergenic region [nr-271106-contam.fasta] YNL058C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene; Ynl058cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Ynl2433p [nr-271106-contam.fasta] YNL058C SGDID:S000005003, Chr XIV from 516715-515765, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] Vacuolar membrane protein YNL058C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNL058C PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YNL058C SGDID:S000005003, Chr XIV from 516713-515763, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene" [yeast-030211-contam.fasta] YNL058C SGDID:S000005003, Chr XIV from 516713-515763, Genome Release 64-2-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to vacuole; not an essential gene; YNL058C has a paralog, PRM5, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
Organism:	Saccharomyces cerevisiae
Length:	316 amino acids
Gene Ontology:
Cellular Component:	fungal-type vacuole [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKNFIPSV SLVRRDLPTL VTTTTSSTAL SKPTSSVVSE TSSKSLPSLT SSAFSTSSGA  60
   61 TSSSSLIVAS ITPPSTAGNP FILNAADKPN GTVYIAVGAV IGAIFISILI WWLVSSYLSR 120
  121 RFTMTNSYAN DSKNLYRGHH KHSSSLQSNP FDINDEKSYM QDDWDSMSQL ESSQYEDAAS 180
  181 PFNPIQDPFT DNRRSLFISP TLQVSQYEKS HSRHQSKDTN IFIDDPFLYV GTYLEEEEEE 240
  241 EEERKLNLNR PQRAASPERK EKKINSMEGY HKRNQSSLGL IPVASATSNT SSPKKAHKRQ 300
  301 APSMFLDDVL NGREII

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	VAM3	sample: hx3	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX11 - both fusion and trans-SNARE complex formation take place.	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control).	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX14 - mixture in detergent (control).	Hao Xu, et al. (2010)
View Run	None Entered	#17 Mitotic Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	TWF1	YNL058C	1	Unpublished Fields Lab Data
View Screen	UBC7	YNL058C	1	Unpublished Fields Lab Data
View Screen	HMT1	YNL058C	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YNL058C	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..316]	deduced	N/A	No confident structure predictions are available.
2	View Details	[208..316]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2