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Protein Overview: RNA1

General Information:
Name(s) found: RNA1 / YMR235C [SGD]
Description(s) found:
Found 24 descriptions.
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  • GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: rRNA export from nucleus [IMPLink to PubMed article]
    ribosomal subunit export from nucleus [IMPLink to PubMed article]
    RNA import into nucleus [IMPLink to PubMed article]
    rRNA metabolic process [IMPLink to PubMed article]
    protein import into nucleus [IDALink to PubMed article]
    Molecular Function: Ran GTPase activator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLHFVPQH EEEQVYSISG KALKLTTSDD IKPYLEELAA LKTCTKLDLS GNTIGTEASE  60
   61 ALAKCIAENT QVRESLVEVN FADLYTSRLV DEVVDSLKFL LPVLLKCPHL EIVNLSDNAF 120
  121 GLRTIELLED YIAHAVNIKH LILSNNGMGP FAGERIGKAL FHLAQNKKAA SKPFLETFIC 180
  181 GRNRLENGSA VYLALGLKSH SEGLKVVKLY QNGIRPKGVA TLIHYGLQYL KNLEILDLQD 240
  241 NTFTKHASLI LAKALPTWKD SLFELNLNDC LLKTAGSDEV FKVFTEVKFP NLHVLKFEYN 300
  301 EMAQETIEVS FLPAMEKGNL PELEKLEING NRLDEDSDAL DLLQSKFDDL EVDDFEEVDS 360
  361 EDEEGEDEED EDEDEKLEEI ETERLEKELL EVQVDDLAER LAETEIK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) CYS3 RNA1
    View Details Gavin AC, et al. (2002) ADE4 CYS3 RNA1
    View Details Ho Y, et al. (2002) CAR1 GDI1 GSP1 GSP2 HOM3 KGD1 MOG1 RIC1 RNA1 SRM1 YPT6 YRB1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RNA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 609.228787 Rna1p (RanGAP1), N-terminal domain
    2 View Details [196..340] PSI-BLAST 609.228787 Rna1p (RanGAP1), N-terminal domain
    3 View Details [341..407] PSI-BLAST 6.0 No description for 1k14A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.665591019824 bayes_pls_golite062009
  • Ran GTPase activator activity
    		•  2.34047639993996 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.29984527283876 bayes_pls_golite062009
  • protein binding
    		•  1.61093336454573 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.2949624636683 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.28868732384901 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.2181060000102 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.20424046001063 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.08702516953191 bayes_pls_golite062009
  • ligase activity
    		•  1.06832436797027 bayes_pls_golite062009
  • actin binding
    		•  0.79104197850666 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.709760900885283 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.283509641791735 bayes_pls_golite062009
  • catalytic activity
    		•  0.143741655309638 bayes_pls_golite062009
  • tropomyosin binding
    		•  0.102409833136912 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle