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Protein Overview: VPS20

General Information:
Name(s) found: VPS20 / YMR077C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 221 amino acids

    Gene Ontology:
    Cellular Component: ESCRT III complex [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [ICLink to PubMed article]
    late endosome to vacuole transport [IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQKSSKVHI TKTDRAILEV KRSKDEIHKF TRRTDNLILV EKSQLKDLIR KNPENYKSNM  60
   61 KVRFLLKRIH YQEHLLQQAS DQLINLENMV STLEFKMVEK QFINGLKNGN EILKKLNKEF 120
  121 SNVDELMDDV QDQIAYQNEI NETLSRSLVG TSNYEDDLDK ELDALESELN PEKMNNAKVA 180
  181 NMPSTEGLPS LPQGEQTEQK EREEFATEER SDTKEPLALL S

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) DID4 SNF7 SRN2 VPS20 VPS24 VPS25 VPS36

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VPS20 and SNF7 Huh WK, et al. (2003)
    View Data VPS20 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..221] PSI-BLAST 12.69897 Heavy meromyosin subfragment


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle