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The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin moiety, or multiple ubiquitin moieties, to the protein. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein. The process of directing proteins towards a membrane using signals contained within the protein, occurring during ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway. The process of directing proteins towards the vacuole using signals contained within the protein, occurring during protein catabolism via the multivesicular body (MVB) pathway. The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Acc: GO:0043162
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
Synonyms:
  • ubiquitin-dependent protein catabolism via the MVB pathway
  • ubiquitin-dependent protein breakdown via the multivesicular body pathway
  • ubiquitin-dependent protein degradation via the multivesicular body pathway
  • ubiquitin-dependent protein catabolic process via the MVB pathway
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 46 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle