Protein Overview: YMR045C

General Information:
Name(s) found:	YMR045C [SGD]
Description(s) found: Found 17 descriptions. SHOW ALL	Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes [SGD]
Organism:	Saccharomyces cerevisiae
Length:	1755 amino acids
Gene Ontology:
Cellular Component:	retrotransposon nucleocapsid [ISS]
Biological Process:	transposition, RNA-mediated [ISS]
Molecular Function:	DNA-directed DNA polymerase activity [ISS] RNA-directed DNA polymerase activity [ISS] RNA binding [ISS] protein binding [ISS] ribonuclease activity [ISS] peptidase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESQQLSQHS PISHGSACAS VTSKEVQTTQ DPLDISASKT EECEKVSTQA NSQQPTTPLS  60
   61 SAVPENHHHA SPQAAQVPLP QNGPYPQQRM MNTQQANISG WPVYGHPSLM PYPPYQMSPM 120
  121 YAPPGAQSQF TQYPQYVGTH LNTPSPESGN SFPDSSSAKS NMTSTNQHVR PPPILTSPND 180
  181 FLNWVKIYIK FLQNSNLGDI IPTATRKAVR QMTDDELTFL CHTFQLFAPS QFLPPWVKDI 240
  241 LSVDYTDIMK ILSKSINKMQ SDTQEVNDIT TLATLHYNGS TPADAFEAEV TNILDRLNNN 300
  301 GIPINNKVAC QFIMRGLSGE YKFLRYARHR CIHMTVADLF SDIHSMYEEQ QESKRNKSTH 360
  361 RRSPSDEKKD SRTYTNTTKP KSITRNSQKP NNSQSRTARA HNVSTFNNSP GPDNDLIRGS 420
  421 TTEPIQLKNT HDLHLGQELT ESTVNHTNHS DDKLPGHLLL DSGASRTLIR SAHHIHSASS 480
  481 NPDINVVDAQ KRNIPINAIG DLQFHFQDNT KTSIKVLHTP NIAYDLLSLN ELAAVDITAC 540
  541 FTKNVLERSD GTVLAPIVKY GDFYWVSKKY LLPSNISVPT INNVHTSEST RKYPYPFIHR 600
  601 MLAHANAQTI RYSLKNNTIT YFNESDVDWS SAIDYQCPDC LIGKSTKHRH IKGSRLKYQN 660
  661 SYEPFQYLHT DIFGPVHNLP KSAPSYFISF TDETTKFRWV YPLHDRREDS ILDVFTTILA 720
  721 FIKNQFQASV LVIQMDRGSE YTNRTLHKFL EKNGITPCYT TTADSRAHGV AERLNRTLLD 780
  781 DCRTQLQCSG LPNHLWFSAI EFSTIVRNSL ASPKSKKSAR QHAGLAGLDI STLLPFGQPV 840
  841 IVNDHNPNSK IHPRGIPGYA LHPSRNSYGY IIYLPSLKKT VDTTNYVILQ GKESRLDQFN 900
  901 YDALTFDEDL NRLTASYHSF IASNEIQQSN DLNIESDHDF QSDIELHPEQ LRNVLSKAVS 960
  961 PTDSTPPSTH TEDSKRVSKT NIRAPREVDP NISESNILPS KKRSSTPQIS DIESTGSGGM1020
 1021 HRLDVPLLAP MSQSNTHESS HASKSKDFRH SDSYSDNETN HTNVPISSTG GTNNKTVPQT1080
 1081 SEQETEKRII HRSPSIDTSS SESNSLHHVV PIKTSDTCPK ENTEESIIAD LPLPDLPPEP1140
 1141 PTELSDSFKE LPPINSRQTN SSLGGIGDSN AYTTINSKKR SLEDNETEIK VSRDTWNTKN1200
 1201 MRSLEPPRSK KRIHLIAAVK AVKSIKPIRT TLRYDEAITY NKDIKEKEKY IEAYHKEVNQ1260
 1261 LLKMKTWDTD KYYDRKEIDP KRVINSMFIF NRKRDGTHKA RFVARGDIQH PDTYDSGMQS1320
 1321 NTVHHYALMT SLSLALDNNY YITQLDISSA YLYADIKEEL YIRPPPHLGM NDKLIRLKKS1380
 1381 LYGLKQSGAN WYETIKSYLI KQCGMEEVRG WSCVFENSQV TICLFVDDMV LFSKNLNSNK1440
 1441 RIIDKLKMQY DTKIINLGES DEEIQYDILG LEIKYQRGKY MKLGMENSLT EKIPKLNVPL1500
 1501 NPKGRKLSAP GQPGLYIDQQ ELELEEDDYK MKVHEMQKLI GLASYVGYKF RFDLLYYINT1560
 1561 LAQHILFPSK QVLDMTYELI QFIWNTRDKQ LIWHKSKPVK PTNKLVVISD ASYGNQPYYK1620
 1621 SQIGNIYLLN GKVIGGKSTK ASLTCTSTTE AEIHAISESV PLLNNLSYLI QELDKKPITK1680
 1681 GLLTDSKSTI SIIISNNEEK FRNRFFGTKA MRLRDEVSGN HLHVCYIETK KNIADVMTKP1740
 1741 LPIKTFKLLT NKWIH

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		YBR012W-B YDR210C-C YDR210C-D YER160C YFL002W-A, YGR161W-B YGR027W-B YHR214C-B YJR027W YLR157C-B YMR045C YMR050C YOR343W-A YOR343W-B

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	RLF2	phosphorylation data - cascade search	Green EM, et al (2005)
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#11 Mitotic Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: YMR045C

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: