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Protein Overview: YLR419W

General Information:
Name(s) found: YLR419W [SGD]
Description(s) found:
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  • gi|74644973|sp|Q06698.1|YL419_YEAST RecName: Full=Putative ATP-dependent RNA helicase YLR419W [NCBI NR]
  • gi|632671|gb|AAB67492.1| Ylr419wp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6323451|ref|NP_013523.1| Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene; Ylr419wp [Sacch [NCBI NR]
  • pir||S59384 hypothetical protein YLR419w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Putative ATP-dependent RNA helicase YLR419W OS=Saccharomyces cerevisiae GN=YLR419W PE=1 SV=1 [Swiss-Prot]
  • Putative helicase [mips]
  • Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene [SGD]
  • YLR419W, Chr XII from 958423-962730 [yeast_orfs2]
  • Chr XII from 958423-962730 [yeastorf3.fasta]
  • >Q06698 (Q06698) Similar to SEVERAL pre-mRNA splicing factors [4932.FASTACCERV.txt]
  • YLR419W SGDID:S0004411, Chr XII from 958424-962731, Uncharacterized ORF [yeastflysequest.fasta]
  • Ylr419wp [Saccharomyces cerevisiae]gi|1363750|pir||S59384 hypothetical protein YLR419w - yeast (Saccharomyces cerevisiae)gi|632671|gb|AAB67492.1| Ylr419wp [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas]
  • (Q06698) Ylr419wp [cerv4932.FASTAC]
  • YLR419W SGDID:S000004411, Chr XII from 958424-962731, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YLR419W SGDID:S000004411, Chr XII from 958425-962732, Uncharacterized ORF, "Putative helicase with limited sequence similarity to human Rb protein; localized to the cytoplasm and the mitochondria; YLR419W is not an essential gene" [yeast-contam.fasta]
  • YLR419W SGDID:S000004411, Chr XII from 958425-962732, Uncharacterized ORF, "Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Y [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Putative ATP-dependent RNA helicase YLR419W [nr-271106-contam.fasta]
  • Putative helicase with limited sequence similarity to human Rb protein; localized to the cytoplasm and the mitochondria; YLR419W is not an essential gene; Ylr419wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Ylr419wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YLR419W SGDID:S000004411, Chr XII from 958425-962732, Uncharacterized ORF, "Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Putative ATP-dependent RNA helicase YLR419W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR419W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YLR419W SGDID:S000004411, Chr XII from 958428-962735, Genome Release 64-1-1, Uncharacterized ORF, "Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene" [yeast-030211-contam.fasta]
  • YLR419W SGDID:S000004411, Chr XII from 958428-962735, Genome Release 64-2-1, Uncharacterized ORF, "Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene" [20141208_orf_trans.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1435 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKTKNNSK SSTPVNDVPT TAGKKKAKGK KGQEPEPEDD KRAKQQSNRA KVTSTASWTG  60
   61 KLPHTILHET CQKRKWNKVE YDMKKIGDKG FIAIAVLSFT DPKTKETLTA RMNDPTYDKA 120
  121 SGKGLVIPQE TPIEARHMAS TIALYRIAYN TNLHMMLPPN HRKTWYALDD FRKDNLKTDE 180
  181 KRINKLFDLD PFKTMVEDRK LKAQREKEQV AQNNQAQKEQ VARTILSSHG GISSSGKDRQ 240
  241 ERKVASHKNS HNPSLVRFPK KVWENSIFVD LDESSRQLIE TSLKEKIDWQ AKKISHKNET 300
  301 IAENREDLKA KLLTLQFRPK HVEEAMLYKD PLSFLLFNLP EDDLPPFFHK KKGDTKNKVE 360
  361 ITNLPLSTRM IVERLTEIGV SSDEALLALQ QNDMNENEAA GFLTREILPT LNSNTNEPVS 420
  421 ETESIECWNQ ELESLESIYE GCVMDAKEDS HYTLNLIEKL KIKLKVYRTK NYPASLPGIV 480
  481 VSTFDKNYKL PDYIKKQILT RLLHYLQEGN LIGDMLVYHI YEWLKENISK IIDNPGPLIP 540
  541 DSDSKGAINK RNISNGKRSI NNSSSRKFTK TTISEDTLSV LREEYTKRIK SSEYKSMQLV 600
  601 REQLPAWKKQ KVIIDIINKN EVVLITGETG SGKSTQVVQF ILDFLQKEKG DFGKTKIVCT 660
  661 QPRRISAIGL AERVSDERCV TCGEEVGYVI RGVNKTKAST RIKFMTTGVL VRLLQNARTM 720
  721 LENTIVVIDE VHERSIDTDL IVTLMKNLLH RVRGMKIVLM SATVNVDLFK KFFPGLATCH 780
  781 IEGRTFPITD YFLEDILSDL DFKIKREKAL SYDDDSVDER NNDDQYLKPR ADSKFFTSGQ 840
  841 INYDLLCQVV EYVHKRLKAA NDNGSIIVFL PGVGEINKCC NLLANKSNEA DFMVLPLHSA 900
  901 LTPEDQKRVF KKYHGKRKVV VSTNIAETSI TIDDCVATID TGRAKSMFYN PKDNTTKLIE 960
  961 SFISKAEVKQ RRGRAGRVRE GLSYKLFSKN LYENDMISMP IPEIKRIPLE SLYLSVKAMG1020
 1021 IKDVKAFLST ALDAPPLPAL QKAERILTTI GLVDESDKSL TQLGQFISLM PVMDSKHGKL1080
 1081 LIYGILFGCT DISVLLVSIL GIGVLPFIGG FENREKIKKL LCKYESRGDL FAVLEIVRDY1140
 1141 FKIKDSSIKR KYLRDNLLSY NKINEIKSST AQYYSILKDV GFLPMDYKVG SISDLNRNER1200
 1201 NFDILRAILT GAFYPHIARV QLPDVKYLST SSGAVEKDPE AKMIKYWIRS EEYQDKLEEY1260
 1261 KTKISQETQK VDLEDLPLPA TRAFIHPSSV LFSTNSVNLE DAKLLSEVDG PISRQSKIPT1320
 1321 VVKYPFVLFT TSQVTNKLYL RDLTPTTTLS LLLFGGAISY DIGGTIHSPG IVVDNWLPIR1380
 1381 TWCKNGVLIK ELRTQLDEAI RKKLESPDYA KKSQIDNSGA DKTLKIVEKI IASEQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CDC6 HSF1 YLR419W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CAB4 No Comments Hazbun TR, et al. (2003)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YLR419W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] deduced N/A No confident structure predictions are available.
    2 View Details [123..249] MSA 1.055994 View MSA. No confident structure predictions are available.
    3 View Details [250..354] deduced N/A No confident structure predictions are available.
    4 View Details [355..411] Pfam 5.207608 UBA/TS-N domain No confident structure predictions are available.
    5 View Details [412..567] MSA 4.45499 View MSA. No confident structure predictions are available.
    6 View Details [568..818] PSI-BLAST 46.154902 Putative DEAD box RNA helicase
    7 View Details [819..999] PSI-BLAST 46.154902 Putative DEAD box RNA helicase
    8 View Details [1000..1309] MSA 6.520942 View MSA. No confident structure predictions are available.
    9 View Details [1310..1435] MSA 2.05299 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • ligase activity
    		•  3.21813427394508 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.90240103975315 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  2.70136670663165 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.00108891190944 bayes_pls_golite062009
  • binding
    		•  1.58040548738005 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.12859634143666 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.04712388093172 bayes_pls_golite062009
  • DNA binding
    		•  0.959326949445296 bayes_pls_golite062009
  • catalytic activity
    		•  0.843965854182766 bayes_pls_golite062009
  • protein binding
    		•  0.601985684548872 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.280767588028274 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.280767588028274 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.279296868168006 bayes_pls_golite062009
  • transferase activity
    		•  0.130846769102963 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.10678738084258 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0748111925362236 bayes_pls_golite062009
  • kinase activity
    		•  0.00493573337799813 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle