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Protein Overview: CHS5

General Information:
Name(s) found: CHS5 / YLR330W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 671 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: cellular bud site selection [IMPLink to PubMed article]
    conjugation with cellular fusion [IMPLink to PubMed article]
    Golgi to plasma membrane transport [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    cell wall chitin catabolic process [IMPLink to PubMed article]
    ascospore wall assembly [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSVDVLLTV GKLDASLALL TTQDHHVIEF PTVLLPENVK AGSIIKMQVS QNLEEEKKQR  60
   61 NHFKSIQAKI LEKYGTHKPE SPVLKIVNVT QTSCVLAWDP LKLGSAKLKS LILYRKGIRS 120
  121 MVIPNPFKVT TTKISGLSVD TPYEFQLKLI TTSGTLWSEK VILRTHKMTD MSGITVCLGP 180
  181 LDPLKEISDL QISQCLSHIG ARPLQRHVAI DTTHFVCNDL DNEESNEELI RAKHNNIPIV 240
  241 RPEWVRACEV EKRIVGVRGF YLDADQSILK NYTFPPVNEE ELSYSKENEP VAEVADENKM 300
  301 PEDTTDVEQV ASPNDNESNP SEAKEQGEKS GHETAPVSPV EDPLHASTAL ENETTIETVN 360
  361 PSVRSLKSEP VGTPNIEENK ADSSAEAVVE EPNEAVAESS PNEEATGQKS EDTDTHSNEQ 420
  421 ADNGFVQTEE VAENNITTES AGENNEPADD AAMEFGRPEA EIETPEVNES IEDANEPAED 480
  481 SNEPVEDSNK PVKDSNKPVE DSNKPVEDSN KPVEDSNKPV EDANEPVEDT SEPVEDAGEP 540
  541 VQETNEFTTD IASPRHQEED IELEAEPKDA TESVAVEPSN EDVKPEEKGS EAEDDINNVS 600
  601 KEAASGESTT HQKTEASASL ESSAVTEEQE TTEAEVNTDD VLSTKEAKKN TGNSNSNKKK 660
  661 NKKNKKKGKK K

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BCH1 BCH2 CHS5
    View Details Krogan NJ, et al. (2006) BCH1 BCH2 CHS5 LAP2 MAE1
    View Details Gavin AC, et al. (2006) BCH1 BUD7 CHS5 CHS6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CHS5 and CHC1 Huh WK, et al. (2003)
    View Data CHS5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [81..361] ab initio 11.76 No description for 1jv2B was found.
    3 View Details [362..501] ab initio 11.76 No description for 1jv2B was found.
    4 View Details [502..588] ab initio 11.76 No description for 1jv2B was found.
    5 View Details [589..671] ab initio 13.27 No description for 1l8mA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle