Protein Overview: PEX30

General Information:
Name(s) found:	PEX30 / YLR324W [SGD]
Description(s) found: Found 23 descriptions. SHOW ALL	Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	523 amino acids
Gene Ontology:
Cellular Component:	peroxisome [IDA] integral to peroxisomal membrane [IDA]
Biological Process:	peroxisome organization [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGNTTNVHE TRAKFAETLQ PRIGGNTTKV IRAALEKNEA ESGVSEDNDN GSLEKVNVAT  60
   61 SPLLTSTPPT ISKALVKLYP YLILIDEFLN VVTWTGKNIW SSVLMLCLFI TTVEYFETLV 120
  121 KYFGHLAIIA ILWGYSLLDN YIEGTLSSSP TLEDIALLMN RVSLKSDILL SPMVNLGTQD 180
  181 IQRLLYTTVI LSPIYVMITW LLLPPRSLML MVGMFLLTYH SPWSKVARRL LWKFKIVRLL 240
  241 VFYVTGLDLG GINKDQGIFA TVQKQVKKLA STENSNGVLS DSKPIRFTYV LYENQRRWLG 300
  301 IGWKPSMLSY ERTPWTDEFL NEAPSPENFH LPEETNTMVW RWVDKTWRLD MTNDGAIQVP 360
  361 NSKARTSADP SPDEGFIYYD NTWKKPSKED SFSKYTRRRR WVRTAELVKT SDFDESVINS 420
  421 NRNSAIEQKV EENSTNGLTA EQELGSNKQE KDNAKKVGEP TTEETKEFAE ASNINEGEFE 480
  481 RISSTDEEVL KSRARDRLAK VLDDTEEKEQ SNPTIGRDSK KAV

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		INP1 INP2 PEX13 PEX30

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	UBC7	PEX30	1	Unpublished Fields Lab Data
View Screen	ILM1	PEX30	1	Lockshon D, et al. (2006)

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	PEX30 and PEX3	Huh WK, et al. (2003)
View Data	PEX30	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..282]	deduced	N/A	No confident structure predictions are available.
2	View Details	[283..436]	MSA	1.005997	View MSA. No confident structure predictions are available.
3	View Details	[437..523]	deduced	N/A	No confident structure predictions are available.
4	View Details	[421..523]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2